Browsing by author "von Loga, Katharina"

Now showing items 1-2 of 2

Computational Image Analysis of T-Cell Infiltrates in Resectable Gastric Cancer: Association with Survival and Molecular Subtypes.

Challoner, BR; von Loga, K; Woolston, A; Griffiths, B; Sivamanoharan, N; Semiannikova, M; Newey, A; Barber, LJ; Mansfield, D; Hewitt, LC; Saito, Y; Davarzani, N; Starling, N; Melcher, A; Grabsch, HI; Gerlinger, M (2021-01)

Background Gastric and gastro-esophageal junction cancers (GCs) frequently recur after resection, but markers to predict recurrence risk are missing. T-cell infiltrates have been validated as prognostic markers in other ...
Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer.

von Loga, K; Woolston, A; Punta, M; Barber, LJ; Griffiths, B; Semiannikova, M; Spain, G; Challoner, B; Fenwick, K; Simon, R; Marx, A; Sauter, G; Lise, S; Matthews, N; Gerlinger, M (2020-01-16)

Mismatch repair deficient (dMMR) gastro-oesophageal adenocarcinomas (GOAs) show better outcomes than their MMR-proficient counterparts and high immunotherapy sensitivity. The hypermutator-phenotype of dMMR tumours theoretically ...

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