Now showing items 1-2 of 2

    • CTCF mediates insulator function at the CFTR locus 

      Blackledge, NP; Carter, EJ; Evans, JR; Lawson, V; Rowntree, RK; Harris, A (PORTLAND PRESS LTD, 2007-12-01)
      Regulatory elements that lie outside the basal promoter of a gene may be revealed by local changes in chromatin structure and histone modifications. The promoter of the CFTR (cystic fibrosis transmembrane conductance ...
    • Early growth response 2 regulates the survival of thymocytes during positive selection 

      Lawson, VJ; Weston, K; Maurice, D (WILEY-V C H VERLAG GMBH, 2010-01)
      The early growth response (Egr) transcription factor family regulates multiple steps during T-cell development. We examine here the role played by Egr2 in positive selection. in double-positive cells, Egr2 is upregulated ...