Now showing items 1673-1692 of 3198

    • Magnetic resonance imaging in precision radiation therapy for lung cancer. 

      Bainbridge, H; Salem, A; Tijssen, RHN; Dubec, M; Wetscherek, A; Van Es, C; Belderbos, J; Faivre-Finn, C; McDonald, F; lung tumour site group of the international Atlantic MR-Linac Consortium (2017-12)
      Radiotherapy remains the cornerstone of curative treatment for inoperable locally advanced lung cancer, given concomitantly with platinum-based chemotherapy. With poor overall survival, research efforts continue to explore ...
    • Magnetic resonance imaging of the low rectum: defining the radiological anatomy. 

      Salerno, G; Daniels, IR; Brown, G (2006-09)
      Low rectal cancer provides a particular surgical challenge of local tumour control and sphincter preservation. Histopathological studies have shown that an involved circumferential resection margin (CRM) and depth of ...
    • Magnetic Resonance Imaging-Based Assessment of Breast Cancer-Related Lymphoedema Tissue Composition. 

      Borri, M; Gordon, KD; Hughes, JC; Scurr, ED; Koh, D-M; Leach, MO; Mortimer, PS; Schmidt, MA (2017-09)
      OBJECTIVES: The aim of this study was to propose a magnetic resonance imaging acquisition and analysis protocol that uses image segmentation to measure and depict fluid, fat, and muscle volumes in breast cancer-related ...
    • Magnetic Resonance Imaging-Guided Adaptive Radiation Therapy: A "Game Changer" for Prostate Treatment? 

      Pathmanathan, AU; van As, NJ; Kerkmeijer, LGW; Christodouleas, J; Lawton, CAF; Vesprini, D; van der Heide, UA; Frank, SJ; Nill, S; Oelfke, U; van Herk, M; Li, XA; Mittauer, K; Ritter, M; Choudhury, A; Tree, AC (2018-02-01)
      Radiation therapy to the prostate involves increasingly sophisticated delivery techniques and changing fractionation schedules. With a low estimated α/β ratio, a larger dose per fraction would be beneficial, with moderate ...
    • Magnetic Resonance Spectroscopy (MRS)-Based Methods for Examining Cancer Metabolism in Response to Oncogenic Kinase Drug Treatment. 

      Chung, Y-L (2017)
      Magnetic resonance spectroscopy (MRS) is an analytical technique that has been extensively used to examine reprogrammed metabolism and treatment response in cancer cells and solid tumors both in vivo and ex vivo. High-resolution ...
    • Magnetic Resonance Spectroscopy to Study Glycolytic Metabolism During Autophagy. 

      Chung, Y-L; Leach, MO; Eykyn, TR (2017)
      Cancer cells undergoing starvation- and treatment-induced autophagy were found to exhibit reduced intracellular lactate, reduced rates of steady-state lactate excretion and reduced real-time pyruvate-lactate exchange rates, ...
    • Magnetic Resonance-based Response Assessment and Dose Adaptation in Human Papilloma Virus Positive Tumors of the Oropharynx treated with Radiotherapy (MR-ADAPTOR): An R-IDEAL stage 2a-2b/Bayesian phase II trial. 

      Bahig, H; Yuan, Y; Mohamed, ASR; Brock, KK; Ng, SP; Wang, J; Ding, Y; Hutcheson, K; McCulloch, M; Balter, PA; Lai, SY; Al-Mamgani, A; Sonke, J-J; van der Heide, UA; Nutting, C; Li, XA; Robbins, J; Awan, M; Karam, I; Newbold, K; Harrington, K; Oelfke, U; Bhide, S; Philippens, MEP; Terhaard, CHJ; McPartlin, AJ; Blanchard, P; Garden, AS; Rosenthal, DI; Gunn, GB; Phan, J; Cazoulat, G; Aristophanous, M; McSpadden, KK; Garcia, JA; van den Berg, CAT; Raaijmakers, CPJ; Kerkmeijer, L; Doornaert, P; Blinde, S; Frank, SJ; Fuller, CD (2018-11)
      Background: Current standard radiotherapy for oropharynx cancer (OPC) is associated with high rates of severe toxicities, shown to adversely impact patients' quality of life. Given excellent outcomes of human papilloma ...
    • Magnitude of observer error using cone beam CT for prostate interfraction motion estimation: effect of reducing scan length or increasing exposure. 

      McNair, HA; Harris, EJ; Hansen, VN; Thomas, K; South, C; Hafeez, S; Huddart, R; Dearnaley, DP (2015-10)
      Cone beam CT (CBCT) enables soft-tissue registration to planning CT for position verification in radiotherapy. The aim of this study was to determine the interobserver error (IOE) in prostate position verification using a ...
    • Major Amputations for Extremity Soft-Tissue Sarcoma. 

      Smith, HG; Thomas, JM; Smith, MJF; Hayes, AJ; Strauss, DC (2018-02)
      INTRODUCTION: With modern techniques facilitating limb conservation, amputation for extremity soft-tissue sarcoma (ESTS) is now rare. We sought to determine the indications and outcomes following major amputation for ESTS ...
    • Major Impact of Sampling Methodology on Gene Expression in Estrogen Receptor-Positive Breast Cancer. 

      Gao, Q; López-Knowles, E; U Cheang, MC; Morden, J; Ribas, R; Sidhu, K; Evans, D; Martins, V; Dodson, A; Skene, A; Holcombe, C; Mallon, E; Evans, A; Bliss, JM; Robertson, J; Smith, I; Martin, L-A; Dowsett, M; POETIC Trial Management Group and Trialists (2018-04)
      To investigate the impact of sampling methodology on gene expression data from primary estrogen receptor-positive (ER+) breast cancer biopsies, global gene expression was measured in core-cut biopsies at baseline and surgery ...
    • Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2. 

      Silvestri, V; Barrowdale, D; Mulligan, AM; Neuhausen, SL; Fox, S; Karlan, BY; Mitchell, G; James, P; Thull, DL; Zorn, KK; Carter, NJ; Nathanson, KL; Domchek, SM; Rebbeck, TR; Ramus, SJ; Nussbaum, RL; Olopade, OI; Rantala, J; Yoon, SY; Caligo, MA; Spugnesi, L; Bojesen, A; Pedersen, IS; Thomassen, M; Jensen, UB; Toland, AE; Senter, L; Andrulis, IL; Glendon, G; Hulick, PJ; Imyanitov, EN; Greene, MH; Mai, PL; Singer, CF; Rappaport-Fuerhauser, C; Kramer, G; Vijai, J; Offit, K; Robson, M; Lincoln, A; Jacobs, L; Machackova, E; Foretova, L; Navratilova, M; Vasickova, P; Couch, FJ; Hallberg, E; Ruddy, KJ; Sharma, P; Kim, SW; Teixeira, MR; Pinto, P; Montagna, M; Matricardi, L; Arason, A; Johannsson, OT; Barkardottir, RB; Jakubowska, A; Lubinski, J; Izquierdo, A; Pujana, MA; Balmaña, J; Diez, O; Ivady, G; Papp, J; Olah, E; Kwong, A; Nevanlinna, H; Aittomäki, K; Perez Segura, P; Caldes, T; Van Maerken, T; Poppe, B; Claes, KB; Isaacs, C; Elan, C; Lasset, C; Stoppa-Lyonnet, D; Barjhoux, L; Belotti, M; Meindl, A; Gehrig, A; Sutter, C; Engel, C; Niederacher, D; Steinemann, D; Hahnen, E; Kast, K; Arnold, N; Varon-Mateeva, R; Wand, D; Godwin, AK; Evans, DG; Frost, D; Perkins, J; Adlard, J; Izatt, L; Platte, R; Eeles, R; Ellis, S; Hamann, U; Garber, J; Fostira, F; Fountzilas, G; Pasini, B; Giannini, G; Rizzolo, P; Russo, A; Cortesi, L; Papi, L; Varesco, L; Palli, D; Zanna, I; Savarese, A; Radice, P; Manoukian, S; Peissel, B; Barile, M; Bonanni, B; Viel, A; Pensotti, V; Tommasi, S; Peterlongo, P; Weitzel, JN; Osorio, A; Benitez, J; McGuffog, L; Healey, S; Gerdes, AM; Ejlertsen, B; Hansen, TV; Steele, L; Ding, YC; Tung, N; Janavicius, R; Goldgar, DE; Buys, SS; Daly, MB; Bane, A; Terry, MB; John, EM; Southey, M; Easton, DF; Chenevix-Trench, G; Antoniou, AC; Ottini, L (2016-01)
      BRCA1 and, more commonly, BRCA2 mutations are associated with increased risk of male breast cancer (MBC). However, only a paucity of data exists on the pathology of breast cancers (BCs) in men with BRCA1/2 mutations. Using ...
    • Malignant Peripheral Nerve Sheath Tumor With Divergent Glandular Differentiation. 

      Miki, Y; Thway, K (2017-06)
      Malignant peripheral nerve sheath tumors (MPNST) are soft tissue neoplasms with evidence of nerve sheath differentiation. They usually arise from peripheral nerves or from preexisting benign nerve sheath neoplasms, often ...
    • MALT lymphoma arising on a background of reactive pulmonary lymphoid hyperplasia in a patient with systemic lupus erythematosus 

      Laggner, U; Khiroya, R; Wotherspoon, AC; Desai, SR; Nicholson, AG (Wiley, 2018-03)
    • Mammographic density and ageing: A collaborative pooled analysis of cross-sectional data from 22 countries worldwide. 

      Burton, A; Maskarinec, G; Perez-Gomez, B; Vachon, C; Miao, H; Lajous, M; López-Ridaura, R; Rice, M; Pereira, A; Garmendia, ML; Tamimi, RM; Bertrand, K; Kwong, A; Ursin, G; Lee, E; Qureshi, SA; Ma, H; Vinnicombe, S; Moss, S; Allen, S; Ndumia, R; Vinayak, S; Teo, S-H; Mariapun, S; Fadzli, F; Peplonska, B; Bukowska, A; Nagata, C; Stone, J; Hopper, J; Giles, G; Ozmen, V; Aribal, ME; Schüz, J; Van Gils, CH; Wanders, JOP; Sirous, R; Sirous, M; Hipwell, J; Kim, J; Lee, JW; Dickens, C; Hartman, M; Chia, K-S; Scott, C; Chiarelli, AM; Linton, L; Pollan, M; Flugelman, AA; Salem, D; Kamal, R; Boyd, N; Dos-Santos-Silva, I; McCormack, V (2017-06)
      BACKGROUND: Mammographic density (MD) is one of the strongest breast cancer risk factors. Its age-related characteristics have been studied in women in western countries, but whether these associations apply to women ...
    • Management of breast cancer--part I. 

      Turner, NC; Jones, AL (2008-01)
    • Management of ceritinib therapy and adverse events in patients with ALK-rearranged non-small cell lung cancer. 

      Califano, R; Greystoke, A; Lal, R; Thompson, J; Popat, S (2017-09)
      Anaplastic lymphoma kinase rearrangement (ALK+) occurs in approximately 2-7% of patients with non-small cell lung cancer (NSCLC), contributing to a considerable number of patients with ALK+ NSCLC worldwide. Ceritinib is a ...
    • The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)? 

      Houlston, R (2006-09)
      The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)? Lobular carcinoma in situ was first described over 60 years ago. Despite the long history, it continues to pose ...
    • Management of localized seminoma, stage I-II: SIU/ICUD Consensus Meeting on Germ Cell Tumors (GCT), Shanghai 2009. 

      Warde, P; Huddart, R; Bolton, D; Heidenreich, A; Gilligan, T; Fossa, S (2011-10)
      The treatment of patients with Stage I-II seminoma has changed considerably in the past decade, and in November 2009, an International Consensus meeting was held under the sponsorship of the Union for International Cancer ...