Now showing items 1688-1707 of 4523

    • A Genome-scale CRISPR Screen Identifies the ERBB and mTOR Signaling Networks as Key Determinants of Response to PI3K Inhibition in Pancreatic Cancer. 

      Milton, CK; Self, AJ; Clarke, PA; Banerji, U; Piccioni, F; Root, DE; Whittaker, SR (2020-07)
      KRAS mutation is a key driver of pancreatic cancer and PI3K pathway activity is an additional requirement for Kras-induced tumorigenesis. Clinical trials of PI3K pathway inhibitors in pancreatic cancer have shown limited ...
    • Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance. 

      Pettitt, SJ; Krastev, DB; Brandsma, I; Dréan, A; Song, F; Aleksandrov, R; Harrell, MI; Menon, M; Brough, R; Campbell, J; Frankum, J; Ranes, M; Pemberton, HN; Rafiq, R; Fenwick, K; Swain, A; Guettler, S; Lee, J-M; Swisher, EM; Stoynov, S; Yusa, K; Ashworth, A; Lord, CJ (2018-05-10)
      Although PARP inhibitors (PARPi) target homologous recombination defective tumours, drug resistance frequently emerges, often via poorly understood mechanisms. Here, using genome-wide and high-density CRISPR-Cas9 ...
    • Genome-wide association analysis identifies a meningioma risk locus at 11p15.5. 

      Claus, EB; Cornish, AJ; Broderick, P; Schildkraut, JM; Dobbins, SE; Holroyd, A; Calvocoressi, L; Lu, L; Hansen, HM; Smirnov, I; Walsh, KM; Schramm, J; Hoffmann, P; Nöthen, MM; Jöckel, K-H; Swerdlow, A; Larsen, SB; Johansen, C; Simon, M; Bondy, M; Wrensch, M; Houlston, RS; Wiemels, JL (2018-10)
      <h4>Background</h4>Meningiomas are adult brain tumors originating in the meningeal coverings of the brain and spinal cord, with significant heritable basis. Genome-wide association studies (GWAS) have previously identified ...
    • Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia. 

      Law, PJ; Berndt, SI; Speedy, HE; Camp, NJ; Sava, GP; Skibola, CF; Holroyd, A; Joseph, V; Sunter, NJ; Nieters, A; Bea, S; Monnereau, A; Martin-Garcia, D; Goldin, LR; Clot, G; Teras, LR; Quintela, I; Birmann, BM; Jayne, S; Cozen, W; Majid, A; Smedby, KE; Lan, Q; Dearden, C; Brooks-Wilson, AR; Hall, AG; Purdue, MP; Mainou-Fowler, T; Vajdic, CM; Jackson, GH; Cocco, P; Marr, H; Zhang, Y; Zheng, T; Giles, GG; Lawrence, C; Call, TG; Liebow, M; Melbye, M; Glimelius, B; Mansouri, L; Glenn, M; Curtin, K; Diver, WR; Link, BK; Conde, L; Bracci, PM; Holly, EA; Jackson, RD; Tinker, LF; Benavente, Y; Boffetta, P; Brennan, P; Maynadie, M; McKay, J; Albanes, D; Weinstein, S; Wang, Z; Caporaso, NE; Morton, LM; Severson, RK; Riboli, E; Vineis, P; Vermeulen, RCH; Southey, MC; Milne, RL; Clavel, J; Topka, S; Spinelli, JJ; Kraft, P; Ennas, MG; Summerfield, G; Ferri, GM; Harris, RJ; Miligi, L; Pettitt, AR; North, KE; Allsup, DJ; Fraumeni, JF; Bailey, JR; Offit, K; Pratt, G; Hjalgrim, H; Pepper, C; Chanock, SJ; Fegan, C; Rosenquist, R; de Sanjose, S; Carracedo, A; Dyer, MJS; Catovsky, D; Campo, E; Cerhan, JR; Allan, JM; Rothman, N; Houlston, R; Slager, S (2017-02-06)
      Several chronic lymphocytic leukaemia (CLL) susceptibility loci have been reported; however, much of the heritable risk remains unidentified. Here we perform a meta-analysis of six genome-wide association studies, imputed ...
    • Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. 

      Law, PJ; Sud, A; Mitchell, JS; Henrion, M; Orlando, G; Lenive, O; Broderick, P; Speedy, HE; Johnson, DC; Kaiser, M; Weinhold, N; Cooke, R; Sunter, NJ; Jackson, GH; Summerfield, G; Harris, RJ; Pettitt, AR; Allsup, DJ; Carmichael, J; Bailey, JR; Pratt, G; Rahman, T; Pepper, C; Fegan, C; von Strandmann, EP; Engert, A; Försti, A; Chen, B; Filho, MIDS; Thomsen, H; Hoffmann, P; Noethen, MM; Eisele, L; Jöckel, K-H; Allan, JM; Swerdlow, AJ; Goldschmidt, H; Catovsky, D; Morgan, GJ; Hemminki, K; Houlston, RS (2017-01-23)
      B-cell malignancies (BCM) originate from the same cell of origin, but at different maturation stages and have distinct clinical phenotypes. Although genetic risk variants for individual BCMs have been identified, an agnostic, ...
    • Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer. 

      Ferreira, MA; Gamazon, ER; Al-Ejeh, F; Aittomäki, K; Andrulis, IL; Anton-Culver, H; Arason, A; Arndt, V; Aronson, KJ; Arun, BK; Asseryanis, E; Azzollini, J; Balmaña, J; Barnes, DR; Barrowdale, D; Beckmann, MW; Behrens, S; Benitez, J; Bermisheva, M; Białkowska, K; Blomqvist, C; Bogdanova, NV; Bojesen, SE; Bolla, MK; Borg, A; Brauch, H; Brenner, H; Broeks, A; Burwinkel, B; Caldés, T; Caligo, MA; Campa, D; Campbell, I; Canzian, F; Carter, J; Carter, BD; Castelao, JE; Chang-Claude, J; Chanock, SJ; Christiansen, H; Chung, WK; Claes, KBM; Clarke, CL; EMBRACE Collaborators; GC-HBOC Study Collaborators; GEMO Study Collaborators; Couch, FJ; Cox, A; Cross, SS; Czene, K; Daly, MB; de la Hoya, M; Dennis, J; Devilee, P; Diez, O; Dörk, T; Dunning, AM; Dwek, M; Eccles, DM; Ejlertsen, B; Ellberg, C; Engel, C; Eriksson, M; Fasching, PA; Fletcher, O; Flyger, H; Friedman, E; Frost, D; Gabrielson, M; Gago-Dominguez, M; Ganz, PA; Gapstur, SM; Garber, J; García-Closas, M; García-Sáenz, JA; Gaudet, MM; Giles, GG; Glendon, G; Godwin, AK; Goldberg, MS; Goldgar, DE; González-Neira, A; Greene, MH; Gronwald, J; Guénel, P; Haiman, CA; Hall, P; Hamann, U; He, W; Heyworth, J; Hogervorst, FBL; Hollestelle, A; Hoover, RN; Hopper, JL; Hulick, PJ; Humphreys, K; Imyanitov, EN; ABCTB Investigators; HEBON Investigators; BCFR Investigators; Isaacs, C; Jakimovska, M; Jakubowska, A; James, PA; Janavicius, R; Jankowitz, RC; John, EM; Johnson, N; Joseph, V; Karlan, BY; Khusnutdinova, E; Kiiski, JI; Ko, Y-D; Jones, ME; Konstantopoulou, I; Kristensen, VN; Laitman, Y; Lambrechts, D; Lazaro, C; Leslie, G; Lester, J; Lesueur, F; Lindström, S; Long, J; Loud, JT; Lubiński, J; Makalic, E; Mannermaa, A; Manoochehri, M; Margolin, S; Maurer, T; Mavroudis, D; McGuffog, L; Meindl, A; Menon, U; Michailidou, K; Miller, A; Montagna, M; Moreno, F; Moserle, L; Mulligan, AM; Nathanson, KL; Neuhausen, SL; Nevanlinna, H; Nevelsteen, I; Nielsen, FC; Nikitina-Zake, L; Nussbaum, RL; Offit, K; Olah, E; Olopade, OI; Olsson, H; Osorio, A; Papp, J; Park-Simon, T-W; Parsons, MT; Pedersen, IS; Peixoto, A; Peterlongo, P; Pharoah, PDP; Plaseska-Karanfilska, D; Poppe, B; Presneau, N; Radice, P; Rantala, J; Rennert, G; Risch, HA; Saloustros, E; Sanden, K; Sawyer, EJ; Schmidt, MK; Schmutzler, RK; Sharma, P; Shu, X-O; Simard, J; Singer, CF; Soucy, P; Southey, MC; Spinelli, JJ; Spurdle, AB; Stone, J; Swerdlow, AJ; Tapper, WJ; Taylor, JA; Teixeira, MR; Terry, MB; Teulé, A; Thomassen, M; Thöne, K; Thull, DL; Tischkowitz, M; Toland, AE; Torres, D; Truong, T; Tung, N; Vachon, CM; van Asperen, CJ; van den Ouweland, AMW; van Rensburg, EJ; Vega, A; Viel, A; Wang, Q; Wappenschmidt, B; Weitzel, JN; Wendt, C; Winqvist, R; Yang, XR; Yannoukakos, D; Ziogas, A; Kraft, P; Antoniou, AC; Zheng, W; Easton, DF; Milne, RL; Beesley, J; Chenevix-Trench, G (2019-04-15)
      Genome-wide association studies (GWAS) have identified more than 170 breast cancer susceptibility loci. Here we hypothesize that some risk-associated variants might act in non-breast tissues, specifically adipose tissue ...
    • Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. 

      Lesseur, C; Ferreiro-Iglesias, A; McKay, JD; Bossé, Y; Johansson, M; Gaborieau, V; Landi, MT; Christiani, DC; Caporaso, NC; Bojesen, SE; Amos, CI; Shete, S; Liu, G; Rennert, G; Albanes, D; Aldrich, MC; Tardon, A; Chen, C; Triantafillos, L; Field, JK; Teare, MD; Kiemeney, LA; Diergaarde, B; Ferris, RL; Zienolddiny, S; Lam, S; Olshan, AF; Weissler, MC; Lacko, M; Risch, A; Bickeböller, H; Ness, AR; Thomas, S; Le Marchand, L; Schabath, MB; Wünsch-Filho, V; Tajara, EH; Andrew, AS; Clifford, GM; Lazarus, P; Grankvist, K; Johansson, M; Arnold, S; Melander, O; Brunnström, H; Boccia, S; Cadoni, G; Timens, W; Obeidat, M; Xiao, X; Houlston, RS; Hung, RJ; Brennan, P (2021-03-05)
      Squamous cell carcinomas (SqCC) of the aerodigestive tract have similar etiological risk factors. Although genetic risk variants for individual cancers have been identified, an agnostic, genome-wide search for shared genetic ...
    • Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21. 

      Teerlink, CC; Leongamornlert, D; Dadaev, T; Thomas, A; Farnham, J; Stephenson, RA; Riska, S; McDonnell, SK; Schaid, DJ; Catalona, WJ; Zheng, SL; Cooney, KA; Ray, AM; Zuhlke, KA; Lange, EM; Giles, GG; Southey, MC; Fitzgerald, LM; Rinckleb, A; Luedeke, M; Maier, C; Stanford, JL; Ostrander, EA; Kaikkonen, EM; Sipeky, C; Tammela, T; Schleutker, J; Wiley, KE; Isaacs, SD; Walsh, PC; Isaacs, WB; Xu, J; Cancel-Tassin, G; Cussenot, O; Mandal, D; Laurie, C; Laurie, C; PRACTICAL consortium; International Consortium for Prostate Cancer Genetics; Thibodeau, SN; Eeles, RA; Kote-Jarai, Z; Cannon-Albright, L (2016-08)
      Previous genome-wide association studies (GWAS) of prostate cancer risk focused on cases unselected for family history and have reported over 100 significant associations. The International Consortium for Prostate Cancer ...
    • Genome-Wide Association Studies in Glioma. 

      Kinnersley, B; Houlston, RS; Bondy, ML (2018-04)
      Since the first reports in 2009, genome-wide association studies (GWAS) have been successful in identifying germline variants associated with glioma susceptibility. In this review, we describe a chronological history of ...
    • Genome-wide association studies of cancer: current insights and future perspectives. 

      Sud, A; Kinnersley, B; Houlston, RS (2017-11)
      Genome-wide association studies (GWAS) provide an agnostic approach for investigating the genetic basis of complex diseases. In oncology, GWAS of nearly all common malignancies have been performed, and over 450 genetic ...
    • Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci. 

      Tanskanen, T; van den Berg, L; Välimäki, N; Aavikko, M; Ness-Jensen, E; Hveem, K; Wettergren, Y; Bexe Lindskog, E; Tõnisson, N; Metspalu, A; Silander, K; Orlando, G; Law, PJ; Tuupanen, S; Gylfe, AE; Hänninen, UA; Cajuso, T; Kondelin, J; Sarin, A-P; Pukkala, E; Jousilahti, P; Salomaa, V; Ripatti, S; Palotie, A; Järvinen, H; Renkonen-Sinisalo, L; Lepistö, A; Böhm, J; Mecklin, J-P; Al-Tassan, NA; Palles, C; Martin, L; Barclay, E; Tenesa, A; Farrington, SM; Timofeeva, MN; Meyer, BF; Wakil, SM; Campbell, H; Smith, CG; Idziaszczyk, S; Maughan, TS; Kaplan, R; Kerr, R; Kerr, D; Buchanan, DD; Win, AK; Hopper, J; Jenkins, MA; Newcomb, PA; Gallinger, S; Conti, D; Schumacher, FR; Casey, G; Cheadle, JP; Dunlop, MG; Tomlinson, IP; Houlston, RS; Palin, K; Aaltonen, LA (2018-02)
      Genome-wide association studies have been successful in elucidating the genetic basis of colorectal cancer (CRC), but there remains unexplained variability in genetic risk. To identify new risk variants and to confirm ...
    • Genome-wide association study identifies five susceptibility loci for glioma. 

      Shete, S; Hosking, FJ; Robertson, LB; Dobbins, SE; Sanson, M; Malmer, B; Simon, M; Marie, Y; Boisselier, B; Delattre, J-Y; Hoang-Xuan, K; El Hallani, S; Idbaih, A; Zelenika, D; Andersson, U; Henriksson, R; Bergenheim, AT; Feychting, M; Lönn, S; Ahlbom, A; Schramm, J; Linnebank, M; Hemminki, K; Kumar, R; Hepworth, SJ; Price, A; Armstrong, G; Liu, Y; Gu, X; Yu, R; Lau, C; Schoemaker, M; Muir, K; Swerdlow, A; Lathrop, M; Bondy, M; Houlston, RS (2009-08)
      To identify risk variants for glioma, we conducted a meta-analysis of two genome-wide association studies by genotyping 550K tagging SNPs in a total of 1,878 cases and 3,670 controls, with validation in three additional ...
    • Genome-wide association study identifies multiple risk loci for renal cell carcinoma. 

      Scelo, G; Purdue, MP; Brown, KM; Johansson, M; Wang, Z; Eckel-Passow, JE; Ye, Y; Hofmann, JN; Choi, J; Foll, M; Gaborieau, V; Machiela, MJ; Colli, LM; Li, P; Sampson, JN; Abedi-Ardekani, B; Besse, C; Blanche, H; Boland, A; Burdette, L; Chabrier, A; Durand, G; Le Calvez-Kelm, F; Prokhortchouk, E; Robinot, N; Skryabin, KG; Wozniak, MB; Yeager, M; Basta-Jovanovic, G; Dzamic, Z; Foretova, L; Holcatova, I; Janout, V; Mates, D; Mukeriya, A; Rascu, S; Zaridze, D; Bencko, V; Cybulski, C; Fabianova, E; Jinga, V; Lissowska, J; Lubinski, J; Navratilova, M; Rudnai, P; Szeszenia-Dabrowska, N; Benhamou, S; Cancel-Tassin, G; Cussenot, O; Baglietto, L; Boeing, H; Khaw, K-T; Weiderpass, E; Ljungberg, B; Sitaram, RT; Bruinsma, F; Jordan, SJ; Severi, G; Winship, I; Hveem, K; Vatten, LJ; Fletcher, T; Koppova, K; Larsson, SC; Wolk, A; Banks, RE; Selby, PJ; Easton, DF; Pharoah, P; Andreotti, G; Freeman, LEB; Koutros, S; Albanes, D; Männistö, S; Weinstein, S; Clark, PE; Edwards, TL; Lipworth, L; Gapstur, SM; Stevens, VL; Carol, H; Freedman, ML; Pomerantz, MM; Cho, E; Kraft, P; Preston, MA; Wilson, KM; Michael Gaziano, J; Sesso, HD; Black, A; Freedman, ND; Huang, W-Y; Anema, JG; Kahnoski, RJ; Lane, BR; Noyes, SL; Petillo, D; Teh, BT; Peters, U; White, E; Anderson, GL; Johnson, L; Luo, J; Buring, J; Lee, I-M; Chow, W-H; Moore, LE; Wood, C; Eisen, T; Henrion, M; Larkin, J; Barman, P; Leibovich, BC; Choueiri, TK; Mark Lathrop, G; Rothman, N; Deleuze, J-F; McKay, JD; Parker, AS; Wu, X; Houlston, RS; Brennan, P; Chanock, SJ (2017-06-09)
      Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing ...
    • Genome-wide association study identifies multiple susceptibility loci for multiple myeloma. 

      Mitchell, JS; Li, N; Weinhold, N; Försti, A; Ali, M; van Duin, M; Thorleifsson, G; Johnson, DC; Chen, B; Halvarsson, B-M; Gudbjartsson, DF; Kuiper, R; Stephens, OW; Bertsch, U; Broderick, P; Campo, C; Einsele, H; Gregory, WA; Gullberg, U; Henrion, M; Hillengass, J; Hoffmann, P; Jackson, GH; Johnsson, E; Jöud, M; Kristinsson, SY; Lenhoff, S; Lenive, O; Mellqvist, U-H; Migliorini, G; Nahi, H; Nelander, S; Nickel, J; Nöthen, MM; Rafnar, T; Ross, FM; da Silva Filho, MI; Swaminathan, B; Thomsen, H; Turesson, I; Vangsted, A; Vogel, U; Waage, A; Walker, BA; Wihlborg, A-K; Broyl, A; Davies, FE; Thorsteinsdottir, U; Langer, C; Hansson, M; Kaiser, M; Sonneveld, P; Stefansson, K; Morgan, GJ; Goldschmidt, H; Hemminki, K; Nilsson, B; Houlston, RS (2016-07)
      Multiple myeloma (MM) is a plasma cell malignancy with a significant heritable basis. Genome-wide association studies have transformed our understanding of MM predisposition, but individual studies have had limited power ...
    • A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1. 

      Vijayakrishnan, J; Kumar, R; Henrion, MYR; Moorman, AV; Rachakonda, PS; Hosen, I; da Silva Filho, MI; Holroyd, A; Dobbins, SE; Koehler, R; Thomsen, H; Irving, JA; Allan, JM; Lightfoot, T; Roman, E; Kinsey, SE; Sheridan, E; Thompson, PD; Hoffmann, P; Nöthen, MM; Heilmann-Heimbach, S; Jöckel, KH; Greaves, M; Harrison, CJ; Bartram, CR; Schrappe, M; Stanulla, M; Hemminki, K; Houlston, RS (2017-03)
      Genome-wide association studies (GWASs) have shown that common genetic variation contributes to the heritable risk of childhood acute lymphoblastic leukemia (ALL). To identify new susceptibility loci for the largest subtype ...
    • Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia. 

      Lin, W-Y; Fordham, SE; Sunter, N; Elstob, C; Rahman, T; Willmore, E; Shepherd, C; Strathdee, G; Mainou-Fowler, T; Piddock, R; Mearns, H; Barrow, T; Houlston, RS; Marr, H; Wallis, J; Summerfield, G; Marshall, S; Pettitt, A; Pepper, C; Fegan, C; Forconi, F; Dyer, MJS; Jayne, S; Sellors, A; Schuh, A; Robbe, P; Oscier, D; Bailey, J; Rais, S; Bentley, A; Cawkwell, L; Evans, P; Hillmen, P; Pratt, G; Allsup, DJ; Allan, JM (2021-01-28)
      Prognostication in patients with chronic lymphocytic leukemia (CLL) is challenging due to heterogeneity in clinical course. We hypothesize that constitutional genetic variation affects disease progression and could aid ...
    • Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia. 

      Vijayakrishnan, J; Studd, J; Broderick, P; Kinnersley, B; Holroyd, A; Law, PJ; Kumar, R; Allan, JM; Harrison, CJ; Moorman, AV; Vora, A; Roman, E; Rachakonda, S; Kinsey, SE; Sheridan, E; Thompson, PD; Irving, JA; Koehler, R; Hoffmann, P; Nöthen, MM; Heilmann-Heimbach, S; Jöckel, K-H; Easton, DF; Pharaoh, PDP; Dunning, AM; Peto, J; Canzian, F; Swerdlow, A; Eeles, RA; Kote-Jarai, Z; Muir, K; Pashayan, N; PRACTICAL Consortium; Greaves, M; Zimmerman, M; Bartram, CR; Schrappe, M; Stanulla, M; Hemminki, K; Houlston, RS (2018-04-09)
      Genome-wide association studies (GWAS) have advanced our understanding of susceptibility to B-cell precursor acute lymphoblastic leukemia (BCP-ALL); however, much of the heritable risk remains unidentified. Here, we perform ...
    • A genome-wide association study identifies susceptibility loci for primary central nervous system lymphoma at 6p25.3 and 3p22.1: a LOC network study. 

      Labreche, K; Daniau, M; Sud, A; Law, PJ; Royer-Perron, L; Holroyd, A; Broderick, P; Went, M; Benazra, M; Ahle, G; Soubeyran, P; Taillandier, L; Chinot, OL; Casasnovas, O; Bay, J-O; Jardin, F; Oberic, L; Fabbro, M; Damaj, G; Brion, A; Mokhtari, K; Philippe, C; Sanson, M; Houillier, C; Soussain, C; Hoang-Xuan, K; Houlston, RS; Alentorn, A; LOC Network (2019-05-17)
      <h4>Background</h4>Primary central nervous system lymphoma (PCNSL) is a rare form of extra-nodal non-Hodgkin lymphoma. PCNSL is a distinct subtype of non-Hodgkin lymphoma, with over 95% of tumors belonging to the diffuse ...
    • Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma. 

      Sud, A; Thomsen, H; Orlando, G; Försti, A; Law, PJ; Broderick, P; Cooke, R; Hariri, F; Pastinen, T; Easton, DF; Pharoah, PDP; Dunning, AM; Peto, J; Canzian, F; Eeles, R; Kote-Jarai, Z; Muir, K; Pashayan, N; Campa, D; PRACTICAL Consortium; Hoffmann, P; Nöthen, MM; Jöckel, K-H; von Strandmann, EP; Swerdlow, AJ; Engert, A; Orr, N; Hemminki, K; Houlston, RS (2018-11)
      To further our understanding of inherited susceptibility to Hodgkin lymphoma (HL), we performed a meta-analysis of 7 genome-wide association studies totaling 5325 HL cases and 22 423 control patients. We identify 5 new HL ...
    • Genome-wide association study of anti-Müllerian hormone levels in pre-menopausal women of late reproductive age and relationship with genetic determinants of reproductive lifespan. 

      Ruth, KS; Soares, ALG; Borges, M-C; Eliassen, AH; Hankinson, SE; Jones, ME; Kraft, P; Nichols, HB; Sandler, DP; Schoemaker, MJ; Taylor, JA; Zeleniuch-Jacquotte, A; Lawlor, DA; Swerdlow, AJ; Murray, A (2019-04)
      Anti-Müllerian hormone (AMH) is required for sexual differentiation in the fetus, and in adult females AMH is produced by growing ovarian follicles. Consequently, AMH levels are correlated with ovarian reserve, declining ...