Browsing by title
Now showing items 2131-2150 of 4323
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Intrusive cognitions and anxiety in cancer patients
(PERGAMON-ELSEVIER SCIENCE LTD, 2008-05)Objective: The study aimed to provide information on intrusive cognitions reported by cancer patients and to investigate for the first time whether intrusive imagery is a factor in psychological morbidity. Methods: Matched ... -
Intuitive Gaze-Control of a Robotized Flexible Endoscope
(IEEE, 2018-01-01) -
Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition.
(2015-01)The use of chemical tools to validate clinical targets has gained in popularity over recent years and the importance of understanding the activity, selectivity and mechanism of action of these compounds is well recognized. ... -
Investigating intracranial tumour growth patterns with multiparametric MRI incorporating Gd-DTPA and USPIO-enhanced imaging.
(2016-11)High grade and metastatic brain tumours exhibit considerable spatial variations in proliferation, angiogenesis, invasion, necrosis and oedema. Vascular heterogeneity arising from vascular co-option in regions of invasive ... -
Investigating Low-Velocity Fluid Flow in Tumors with Convection-MRI.
(2018-04)Several distinct fluid flow phenomena occur in solid tumors, including intravascular blood flow and interstitial convection. Interstitial fluid pressure is often raised in solid tumors, which can limit drug delivery. To ... -
Investigating the Contribution of Collagen to the Tumor Biomechanical Phenotype with Noninvasive Magnetic Resonance Elastography.
(2019-11)Increased stiffness in the extracellular matrix (ECM) contributes to tumor progression and metastasis. Therefore, stromal modulating therapies and accompanying biomarkers are being developed to target ECM stiffness. Magnetic ... -
Investigating the effect of a magnetic field on dose distributions at phantom-air interfaces using PRESAGE® 3D dosimeter and Monte Carlo simulations.
(2018-02-26)Dosimetric quality assurance (QA) of the new Elekta Unity (MR-linac) will differ from the QA performed of a conventional linac due to the constant magnetic field, which creates an electron return effect (ERE). In this work ... -
Investigating the heterogeneity of alkylating agents' efficacy and toxicity between sexes: A systematic review and meta-analysis of randomized trials comparing cyclophosphamide and ifosfamide (MAIAGE study).
(2017-08)<h4>Background</h4>A marginal interaction between sex and the type of alkylating agent was observed for event-free survival in the Euro-EWING99-R1 randomized controlled trial (RCT) comparing cyclophosphamide and ifosfamide ... -
Investigating the mehcanisms of drug resistance in gastro-intestinal cancers
(2020-03-31)Despite many effective therapies for gastro-intestinal (GI) cancers, both primary and acquired mechanisms of resistance commonly occur. The subclonal complexity of intra-tumoural heterogeneity in these cancers further ... -
Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis.
(2017-01)Coffee consumption has been shown in some studies to be associated with lower risk of prostate cancer. However, it is unclear if this association is causal or due to confounding or reverse causality. We conducted a Mendelian ... -
Investigating the Vascular Phenotype of Subcutaneously and Orthotopically Propagated PC3 Prostate Cancer Xenografts Using Combined Carbogen Ultrasmall Superparamagnetic Iron Oxide MRI.
(2016-10)The aim of this study was to use the combined carbogen-ultrasmall superparamagnetic iron oxide (CUSPIO) magnetic resonance imaging (MRI) method, which uses spatial correlations in independent susceptibility imaging biomarkers, ... -
An investigation into the effect of extending routine mammographic screening to older women in the United Kingdom on the time it takes to screen
(2002)Objective: To compare the time it takes to screen women aged 65-69 with women age 50-64. Setting: Screening centres participating in the Department of Health funded demonstration study of extending breast screening to women ... -
An investigation into the number of appointment changes and queries arising as a result of extending breast screening to older women in the United Kingdom
(BRITISH MED JOURNAL PUBL GROUP, 2002)Objective: To compare the number of telephone queries and appointment changes requested by women aged 65-69 with women aged 50-64. Setting: Department of Health funded demonstration study of extending breast screening to ... -
An Investigation of Dosimetric Correlates of Acute Toxicity in Prostate Stereotactic Body Radiotherapy: Dose to Urinary Trigone is Associated with Acute Urinary Toxicity.
(2018-09)AIMS:There are limited data on dosimetric correlates of toxicity in stereotactic body radiotherapy (SBRT) for prostate cancer. We aimed to identify potential relationships between dose and toxicity using conventional ... -
Investigation of In Vivo skin stiffness anisotropy in breast cancer related lymphoedema.
(2016-01)There is a limited range of suitable measurement techniques for detecting and assessing breast cancer related lymphoedema (BCRL). This study investigated the suitability of using skin stiffness measurements, with a particular ... -
Investigation of scintillator coated CCDs for medical imaging
(IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 2006-02)We describe the development of a scintillator-coated charge coupled device (CCD) based camera for imaging small volumes of radionuclide uptake in tissues. The high-resolution gamma imager (HRGI) is a collimated, ... -
Investigation of the ability of haplotype association and logistic regression to identify associated susceptibility loci
(WILEY-BLACKWELL PUBLISHING, INC, 2006-11)While finely spaced markers are increasingly being used in case-control association studies in attempts to identify susceptibility loci, not enough is yet known as to the optimal spacing of such markers, their likely power ...
