Browsing by subject "3' Untranslated Regions"

Now showing items 1-3 of 3

    • Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer. 

      Fletcher, CE; Sulpice, E; Combe, S; Shibakawa, A; Leach, DA; Hamilton, MP; Chrysostomou, SL; Sharp, A; Welti, J; Yuan, W; Dart, DA; Knight, E; Ning, J; Francis, JC; Kounatidou, EE; Gaughan, L; Swain, A; Lupold, SE; de Bono, JS; McGuire, SE; Gidrol, X; Bevan, CL (2019-07)
      Androgen receptor (AR) signalling is a key prostate cancer (PC) driver, even in advanced 'castrate-resistant' disease (CRPC). To systematically identify microRNAs (miRs) modulating AR activity in lethal disease, ...

    • Identification of miRSNPs associated with the risk of multiple myeloma. 

      Macauda, A; Calvetti, D; Maccari, G; Hemminki, K; Försti, A; Goldschmidt, H; Weinhold, N; Houlston, R; Andersen, V; Vogel, U; Buda, G; Varkonyi, J; Sureda, A; Martinez Lopez, J; Watek, M; Butrym, A; Sarasquete, ME; Dudziński, M; Jurczyszyn, A; Druzd-Sitek, A; Kruszewski, M; Subocz, E; Petrini, M; Iskierka-Jażdżewska, E; Raźny, M; Szombath, G; Marques, H; Zawirska, D; Chraniuk, D; Halka, J; Hove Jacobsen, SE; Mazur, G; García Sanz, R; Dumontet, C; Moreno, V; Stępień, A; Beider, K; Pelosini, M; Manuel Reis, R; Krawczyk-Kulis, M; Rymko, M; Avet-Loiseau, H; Lesueur, F; Grząśko, N; Ostrovsky, O; Jamroziak, K; Vangsted, AJ; Jerez, A; Tomczak, W; Zaucha, JM; Kadar, K; Sainz, J; Nagler, A; Landi, S; Gemignani, F; Canzian, F (2017-02)
      Multiple myeloma (MM) is a malignancy of plasma cells usually infiltrating the bone marrow, associated with the production of a monoclonal immunoglobulin (M protein) which can be detected in the blood and/or urine. Multiple ...

    • rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk. 

      Liu, J; Lončar, I; Collée, JM; Bolla, MK; Dennis, J; Michailidou, K; Wang, Q; Andrulis, IL; Barile, M; Beckmann, MW; Behrens, S; Benitez, J; Blomqvist, C; Boeckx, B; Bogdanova, NV; Bojesen, SE; Brauch, H; Brennan, P; Brenner, H; Broeks, A; Burwinkel, B; Chang-Claude, J; Chen, S-T; Chenevix-Trench, G; Cheng, CY; Choi, J-Y; Couch, FJ; Cox, A; Cross, SS; Cuk, K; Czene, K; Dörk, T; Dos-Santos-Silva, I; Fasching, PA; Figueroa, J; Flyger, H; García-Closas, M; Giles, GG; Glendon, G; Goldberg, MS; González-Neira, A; Guénel, P; Haiman, CA; Hamann, U; Hart, SN; Hartman, M; Hatse, S; Hopper, JL; Ito, H; Jakubowska, A; Kabisch, M; Kang, D; Kosma, V-M; Kristensen, VN; Le Marchand, L; Lee, E; Li, J; Lophatananon, A; Jan Lubinski; Mannermaa, A; Matsuo, K; Milne, RL; NBCS Collaborators; Neuhausen, SL; Nevanlinna, H; Orr, N; Perez, JIA; Peto, J; Putti, TC; Pylkäs, K; Radice, P; Sangrajrang, S; Sawyer, EJ; Schmidt, MK; Schneeweiss, A; Shen, C-Y; Shrubsole, MJ; Shu, X-O; Simard, J; Southey, MC; Swerdlow, A; Teo, SH; Tessier, DC; Thanasitthichai, S; Tomlinson, I; Torres, D; Truong, T; Tseng, C-C; Vachon, C; Winqvist, R; Wu, AH; Yannoukakos, D; Zheng, W; Hall, P; Dunning, AM; Easton, DF; Hooning, MJ; van den Ouweland, AMW; Martens, JWM; Hollestelle, A (2016-11-15)
      NBS1, also known as NBN, plays an important role in maintaining genomic stability. Interestingly, rs2735383 G > C, located in a microRNA binding site in the 3'-untranslated region (UTR) of NBS1, was shown to be associated ...