Browsing by subject "3-DIMENSIONAL EXTRACELLULAR MATRICES; CAPILLARY LUMEN FORMATION; ADVANCED SOLID TUMORS; GROWTH-FACTOR; PATHOLOGICAL ANGIOGENESIS; CILENGITIDE EMD-121974; VASCULAR DEVELOPMENT; INTEGRIN INHIBITORS; RAC1 ACTIVATION; CRE-RECOMBINASE"
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Endothelial-Rac1 Is Not Required for Tumor Angiogenesis unless alpha v beta 3-Integrin Is Absent
(PUBLIC LIBRARY SCIENCE, 2010-03)Endothelial cell migration is an essential aspect of tumor angiogenesis. Rac1 activity is needed for cell migration in vitro implying a requirement for this molecule in angiogenesis in vivo. However, a precise role for ...