Browsing by subject "3-Hydroxyacyl CoA Dehydrogenases"

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    • SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1. 

      Sebaa, R; Johnson, J; Pileggi, C; Norgren, M; Xuan, J; Sai, Y; Tong, Q; Krystkowiak, I; Bondy-Chorney, E; Davey, NE; Krogan, N; Downey, M; Harper, M-E (2019-07)
      OBJECTIVE:Brown adipose tissue (BAT) is important for thermoregulation in many mammals. Uncoupling protein 1 (UCP1) is the critical regulator of thermogenesis in BAT. Here we aimed to investigate the deacetylation control ...