Now showing items 1-1 of 1

    • Subclonal <i>TP53</i> copy number is associated with prognosis in multiple myeloma. 

      Shah, V; Johnson, DC; Sherborne, AL; Ellis, S; Aldridge, FM; Howard-Reeves, J; Begum, F; Price, A; Kendall, J; Chiecchio, L; Savola, S; Jenner, MW; Drayson, MT; Owen, RG; Gregory, WM; Morgan, GJ; Davies, FE; Houlston, RS; Cook, G; Cairns, DA; Jackson, G; Kaiser, MF; National Cancer Research Institute Haematology Clinical Studies Group (2018-12)
      Multiple myeloma (MM) is a genetically heterogeneous cancer of bone marrow plasma cells with variable outcome. To assess the prognostic relevance of clonal heterogeneity of <i>TP53</i> copy number, we profiled tumors from ...