Now showing items 1-13 of 13

    • Beam selection for stereotactic ablative radiotherapy using Cyberknife with multileaf collimation. 

      Bedford, JL; Ziegenhein, P; Nill, S; Oelfke, U (2019-02)
      The Cyberknife system (Accuray Inc., Sunnyvale, CA) enables radiotherapy using stereotactic ablative body radiotherapy (SABR) with a large number of non-coplanar beam orientations. Recently, a multileaf collimator has also ...
    • Genetic susceptibility to radiation-induced breast cancer after Hodgkin lymphoma. 

      Opstal-van Winden, AWJ; de Haan, HG; Hauptmann, M; Schmidt, MK; Broeks, A; Russell, NS; Janus, CPM; Krol, ADG; van der Baan, FH; De Bruin, ML; van Eggermond, AM; Dennis, J; Anton-Culver, H; Haiman, CA; Sawyer, EJ; Cox, A; Devilee, P; Hooning, MJ; Peto, J; Couch, FJ; Pharoah, P; Orr, N; Easton, DF; Aleman, BMP; Strong, LC; Bhatia, S; Cooke, R; Robison, LL; Swerdlow, AJ; van Leeuwen, FE (2019-03)
      Female Hodgkin lymphoma (HL) patients treated with chest radiotherapy (RT) have a very high risk of breast cancer. The contribution of genetic factors to this risk is unclear. We therefore examined 211 155 germline ...
    • Guideline for PET/CT imaging of neuroendocrine neoplasms with <sup>68</sup>Ga-DOTA-conjugated somatostatin receptor targeting peptides and <sup>18</sup>F-DOPA. 

      Bozkurt, MF; Virgolini, I; Balogova, S; Beheshti, M; Rubello, D; Decristoforo, C; Ambrosini, V; Kjaer, A; Delgado-Bolton, R; Kunikowska, J; Oyen, WJG; Chiti, A; Giammarile, F; Sundin, A; Fanti, S (2017-08)
      Purpose & methods Neuroendocrine neoplasms are a heterogenous group of tumours, for which nuclear medicine plays an important role in the diagnostic work-up as well as in the targeted therapeutic options. This guideline ...
    • Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma. 

      Went, M; Sud, A; Försti, A; Halvarsson, B-M; Weinhold, N; Kimber, S; van Duin, M; Thorleifsson, G; Holroyd, A; Johnson, DC; Li, N; Orlando, G; Law, PJ; Ali, M; Chen, B; Mitchell, JS; Gudbjartsson, DF; Kuiper, R; Stephens, OW; Bertsch, U; Broderick, P; Campo, C; Bandapalli, OR; Einsele, H; Gregory, WA; Gullberg, U; Hillengass, J; Hoffmann, P; Jackson, GH; Jöckel, K-H; Johnsson, E; Kristinsson, SY; Mellqvist, U-H; Nahi, H; Easton, D; Pharoah, P; Dunning, A; Peto, J; Canzian, F; Swerdlow, A; Eeles, RA; Kote-Jarai, Z; Muir, K; Pashayan, N; Nickel, J; Nöthen, MM; Rafnar, T; Ross, FM; da Silva Filho, MI; Thomsen, H; Turesson, I; Vangsted, A; Andersen, NF; Waage, A; Walker, BA; Wihlborg, A-K; Broyl, A; Davies, FE; Thorsteinsdottir, U; Langer, C; Hansson, M; Goldschmidt, H; Kaiser, M; Sonneveld, P; Stefansson, K; Morgan, GJ; Hemminki, K; Nilsson, B; Houlston, RS; PRACTICAL consortium (2018-09-13)
      Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous ...
    • Interlaboratory Reproducibility of a Targeted Metabolomics Platform for Analysis of Human Serum and Plasma. 

      Siskos, AP; Jain, P; Römisch-Margl, W; Bennett, M; Achaintre, D; Asad, Y; Marney, L; Richardson, L; Koulman, A; Griffin, JL; Raynaud, F; Scalbert, A; Adamski, J; Prehn, C; Keun, HC (2017-01)
      A critical question facing the field of metabolomics is whether data obtained from different centers can be effectively compared and combined. An important aspect of this is the interlaboratory precision (reproducibility) ...
    • Monitoring the ERSPC trial. 

      De Koning, HJ; Hakulinen, T; Moss, SM; Adolfsson, J; Smith, PH; Alexander, FE; ERSPC (2003-12)
    • MRI commissioning of 1.5T MR-linac systems - a multi-institutional study. 

      Tijssen, RHN; Philippens, MEP; Paulson, ES; Glitzner, M; Chugh, B; Wetscherek, A; Dubec, M; Wang, J; van der Heide, UA (2019-03)
      BACKGROUND:Magnetic Resonance linear accelerator (MR-linac) systems represent a new type of technology that allows for online MR-guidance for high precision radiotherapy (RT). Currently, the first MR-linac installations ...
    • Online dose reconstruction for tracked volumetric arc therapy: Real-time implementation and offline quality assurance for prostate SBRT. 

      Kamerling, CP; Fast, MF; Ziegenhein, P; Menten, MJ; Nill, S; Oelfke, U (2017-11)
      Purpose Firstly, this study provides a real-time implementation of online dose reconstruction for tracked volumetric arc therapy (VMAT). Secondly, this study describes a novel offline quality assurance tool, based on ...
    • Perspectives on ENCODE. 

      ENCODE Project Consortium; Snyder, MP; Gingeras, TR; Moore, JE; Weng, Z; Gerstein, MB; Ren, B; Hardison, RC; Stamatoyannopoulos, JA; Graveley, BR; Feingold, EA; Pazin, MJ; Pagan, M; Gilchrist, DA; Hitz, BC; Cherry, JM; Bernstein, BE; Mendenhall, EM; Zerbino, DR; Frankish, A; Flicek, P; Myers, RM (2020-07-29)
      The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical regions associated ...
    • seXY: a tool for sex inference from genotype arrays. 

      Qian, DC; Busam, JA; Xiao, X; O'Mara, TA; Eeles, RA; Schumacher, FR; Phelan, CM; Amos, CI (2017-02)
      Motivation Checking concordance between reported sex and genotype-inferred sex is a crucial quality control measure in genome-wide association studies (GWAS). However, limited insights exist regarding the true accuracy of ...
    • The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS). 

      Leach, MO; Eeles, RA; Turnbull, LW; Dixon, AK; Brown, J; Hoff, RJC; Coulthard, A; Dixon, JM; Easton, DF; Evans, DGR; Gilbert, FJ; Hawnaur, J; Hayes, C; Kessar, P; Lakhani, S; Liney, G; Moss, SM; Padhani, AP; Pointon, LJ; Sydenham, M; Walker, LG; Warren, RML; Haites, NE; Morrison, P; Cole, T; Rayter, Z; Donaldson, A; Shere, M; Rankin, J; Goudie, D; Steel, CM; Davidson, R; Chu, C; Ellis, I; Mackay, J; Hodgson, SV; Homfray, T; Douglas, F; Quarrell, OW; Eccles, DM; Gilbert, FG; Crothers, G; Walker, CP; Jones, A; Slack, N; Britton, P; Sheppard, DG; Walsh, J; Whitehouse, G; Teh, W; Rankin, S; Boggis, C; Potterton, J; McLean, L; Gordon, PAL; Rubin, C; Magnetic Resonance Imaging as a Method of Screening for Breast Cancer Advisory Group (2002-09)
      The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS) is in progress. The study design, accrual to date, and related research projects are described. Revised accrual rates ...
    • UK quantitative WB-DWI technical workgroup: consensus meeting recommendations on optimisation, quality control, processing and analysis of quantitative whole-body diffusion-weighted imaging for cancer. 

      Barnes, A; Alonzi, R; Blackledge, M; Charles-Edwards, G; Collins, DJ; Cook, G; Coutts, G; Goh, V; Graves, M; Kelly, C; Koh, D-M; McCallum, H; Miquel, ME; O'Connor, J; Padhani, A; Pearson, R; Priest, A; Rockall, A; Stirling, J; Taylor, S; Tunariu, N; van der Meulen, J; Walls, D; Winfield, J; Punwani, S (2018-01)
      Objective Application of whole body diffusion-weighted MRI (WB-DWI) for oncology are rapidly increasing within both research and routine clinical domains. However, WB-DWI as a quantitative imaging biomarker (QIB) has ...
    • Whole-remnant and maximum-voxel SPECT/CT dosimetry in <sup>131</sup>I-NaI treatments of differentiated thyroid cancer. 

      Mínguez, P; Flux, G; Genollá, J; Delgado, A; Rodeño, E; Sjögreen Gleisner, K (2016-10)
      Purpose To investigate the possible differences between SPECT/CT based whole-remnant and maximum-voxel dosimetry in patients receiving radio-iodine ablation treatment of differentiated thyroid cancer (DTC).Methods Eighteen ...