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    • The evolutionary landscape of colorectal tumorigenesis. 

      Cross, W; Kovac, M; Mustonen, V; Temko, D; Davis, H; Baker, A-M; Biswas, S; Arnold, R; Chegwidden, L; Gatenbee, C; Anderson, AR; Koelzer, VH; Martinez, P; Jiang, X; Domingo, E; Woodcock, DJ; Feng, Y; Kovacova, M; Maughan, T; S:CORT Consortium; Jansen, M; Rodriguez-Justo, M; Ashraf, S; Guy, R; Cunningham, C; East, JE; Wedge, DC; Wang, LM; Palles, C; Heinimann, K; Sottoriva, A; Leedham, SJ; Graham, TA; Tomlinson, IPM (2018-10)
      The evolutionary events that cause colorectal adenomas (benign) to progress to carcinomas (malignant) remain largely undetermined. Using multi-region genome and exome sequencing of 24 benign and malignant colorectal tumours, ...