Now showing items 1-3 of 3

    • Donated chemical probes for open science. 

      Müller, S; Ackloo, S; Arrowsmith, CH; Bauser, M; Baryza, JL; Blagg, J; Böttcher, J; Bountra, C; Brown, PJ; Bunnage, ME; Carter, AJ; Damerell, D; Dötsch, V; Drewry, DH; Edwards, AM; Edwards, J; Elkins, JM; Fischer, C; Frye, SV; Gollner, A; Grimshaw, CE; IJzerman, A; Hanke, T; Hartung, IV; Hitchcock, S; Howe, T; Hughes, TV; Laufer, S; Li, VM; Liras, S; Marsden, BD; Matsui, H; Mathias, J; O'Hagan, RC; Owen, DR; Pande, V; Rauh, D; Rosenberg, SH; Roth, BL; Schneider, NS; Scholten, C; Singh Saikatendu, K; Simeonov, A; Takizawa, M; Tse, C; Thompson, PR; Treiber, DK; Viana, AY; Wells, CI; Willson, TM; Zuercher, WJ; Knapp, S; Mueller-Fahrnow, A (2018-04-20)
      Potent, selective and broadly characterized small molecule modulators of protein function (chemical probes) are powerful research reagents. The pharmaceutical industry has generated many high-quality chemical probes and ...
    • Drug discovery strategies: technologies to accelerate translation from target to drug. 

      Workman, P (2004-11)
      The development of new molecular therapeutics for cancer treatment is based on the identification of molecular abnormalities that drive the malignant process. The discovery of novel molecular targets is made quicker and ...
    • The role of functional and molecular imaging in cancer drug discovery and development. 

      Seddon, BM; Workman, P (2003-01)
      Studies of pharmacokinetics (which is what the body does to the drug) and pharmacodynamics (which is what the drug does to the body) are essential components of the modern process of cancer drug discovery and development. ...