Now showing items 1-10 of 10

    • A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. 

      Wu, L; Shi, W; Long, J; Guo, X; Michailidou, K; Beesley, J; Bolla, MK; Shu, X-O; Lu, Y; Cai, Q; Al-Ejeh, F; Rozali, E; Wang, Q; Dennis, J; Li, B; Zeng, C; Feng, H; Gusev, A; Barfield, RT; Andrulis, IL; Anton-Culver, H; Arndt, V; Aronson, KJ; Auer, PL; Barrdahl, M; Baynes, C; Beckmann, MW; Benitez, J; Bermisheva, M; Blomqvist, C; Bogdanova, NV; Bojesen, SE; Brauch, H; Brenner, H; Brinton, L; Broberg, P; Brucker, SY; Burwinkel, B; Caldés, T; Canzian, F; Carter, BD; Castelao, JE; Chang-Claude, J; Chen, X; Cheng, T-YD; Christiansen, H; Clarke, CL; NBCS Collaborators; Collée, M; Cornelissen, S; Couch, FJ; Cox, D; Cox, A; Cross, SS; Cunningham, JM; Czene, K; Daly, MB; Devilee, P; Doheny, KF; Dörk, T; Dos-Santos-Silva, I; Dumont, M; Dwek, M; Eccles, DM; Eilber, U; Eliassen, AH; Engel, C; Eriksson, M; Fachal, L; Fasching, PA; Figueroa, J; Flesch-Janys, D; Fletcher, O; Flyger, H; Fritschi, L; Gabrielson, M; Gago-Dominguez, M; Gapstur, SM; García-Closas, M; Gaudet, MM; Ghoussaini, M; Giles, GG; Goldberg, MS; Goldgar, DE; González-Neira, A; Guénel, P; Hahnen, E; Haiman, CA; Håkansson, N; Hall, P; Hallberg, E; Hamann, U; Harrington, P; Hein, A; Hicks, B; Hillemanns, P; Hollestelle, A; Hoover, RN; Hopper, JL; Huang, G; Humphreys, K; Hunter, DJ; Jakubowska, A; Janni, W; John, EM; Johnson, N; Jones, K; Jones, ME; Jung, A; Kaaks, R; Kerin, MJ; Khusnutdinova, E; Kosma, V-M; Kristensen, VN; Lambrechts, D; Le Marchand, L; Li, J; Lindström, S; Lissowska, J; Lo, W-Y; Loibl, S; Lubinski, J; Luccarini, C; Lux, MP; MacInnis, RJ; Maishman, T; Kostovska, IM; Mannermaa, A; Manson, JE; Margolin, S; Mavroudis, D; Meijers-Heijboer, H; Meindl, A; Menon, U; Meyer, J; Mulligan, AM; Neuhausen, SL; Nevanlinna, H; Neven, P; Nielsen, SF; Nordestgaard, BG; Olopade, OI; Olson, JE; Olsson, H; Peterlongo, P; Peto, J; Plaseska-Karanfilska, D; Prentice, R; Presneau, N; Pylkäs, K; Rack, B; Radice, P; Rahman, N; Rennert, G; Rennert, HS; Rhenius, V; Romero, A; Romm, J; Rudolph, A; Saloustros, E; Sandler, DP; Sawyer, EJ; Schmidt, MK; Schmutzler, RK; Schneeweiss, A; Scott, RJ; Scott, CG; Seal, S; Shah, M; Shrubsole, MJ; Smeets, A; Southey, MC; Spinelli, JJ; Stone, J; Surowy, H; Swerdlow, AJ; Tamimi, RM; Tapper, W; Taylor, JA; Terry, MB; Tessier, DC; Thomas, A; Thöne, K; Tollenaar, RAEM; Torres, D; Truong, T; Untch, M; Vachon, C; Van Den Berg, D; Vincent, D; Waisfisz, Q; Weinberg, CR; Wendt, C; Whittemore, AS; Wildiers, H; Willett, WC; Winqvist, R; Wolk, A; Xia, L; Yang, XR; Ziogas, A; Ziv, E; kConFab/AOCS Investigators; Dunning, AM; Pharoah, PDP; Simard, J; Milne, RL; Edwards, SL; Kraft, P; Easton, DF; Chenevix-Trench, G; Zheng, W (2018-07)
      The breast cancer risk variants identified in genome-wide association studies explain only a small fraction of the familial relative risk, and the genes responsible for these associations remain largely unknown. To identify ...
    • Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21. 

      Hamdi, Y; Soucy, P; Adoue, V; Michailidou, K; Canisius, S; Lemaçon, A; Droit, A; Andrulis, IL; Anton-Culver, H; Arndt, V; Baynes, C; Blomqvist, C; Bogdanova, NV; Bojesen, SE; Bolla, MK; Bonanni, B; Borresen-Dale, A-L; Brand, JS; Brauch, H; Brenner, H; Broeks, A; Burwinkel, B; Chang-Claude, J; NBCS Collaborators; Couch, FJ; Cox, A; Cross, SS; Czene, K; Darabi, H; Dennis, J; Devilee, P; Dörk, T; Dos-Santos-Silva, I; Eriksson, M; Fasching, PA; Figueroa, J; Flyger, H; García-Closas, M; Giles, GG; Goldberg, MS; González-Neira, A; Grenaker-Alnæs, G; Guénel, P; Haeberle, L; Haiman, CA; Hamann, U; Hallberg, E; Hooning, MJ; Hopper, JL; Jakubowska, A; Jones, M; Kabisch, M; Kataja, V; Lambrechts, D; Le Marchand, L; Lindblom, A; Lubinski, J; Mannermaa, A; Maranian, M; Margolin, S; Marme, F; Milne, RL; Neuhausen, SL; Nevanlinna, H; Neven, P; Olswold, C; Peto, J; Plaseska-Karanfilska, D; Pylkäs, K; Radice, P; Rudolph, A; Sawyer, EJ; Schmidt, MK; Shu, X-O; Southey, MC; Swerdlow, A; Tollenaar, RAEM; Tomlinson, I; Torres, D; Truong, T; Vachon, C; Van Den Ouweland, AMW; Wang, Q; Winqvist, R; kConFab/AOCS Investigators; Zheng, W; Benitez, J; Chenevix-Trench, G; Dunning, AM; Pharoah, PDP; Kristensen, V; Hall, P; Easton, DF; Pastinen, T; Nord, S; Simard, J (2016-12)
      There are significant inter-individual differences in the levels of gene expression. Through modulation of gene expression, cis-acting variants represent an important source of phenotypic variation. Consequently, cis-regulatory ...
    • Combined associations of a polygenic risk score and classical risk factors with breast cancer risk. 

      Kapoor, PM; Mavaddat, N; Choudhury, PP; Wilcox, AN; Lindström, S; Behrens, S; Michailidou, K; Dennis, J; Bolla, MK; Wang, Q; Jung, A; Abu-Ful, Z; Ahearn, T; Andrulis, IL; Anton-Culver, H; Arndt, V; Aronson, KJ; Auer, PL; Freeman, LEB; Becher, H; Beckmann, MW; Beeghly-Fadiel, A; Benitez, J; Bernstein, L; Bojesen, SE; Brauch, H; Brenner, H; Brüning, T; Cai, Q; Campa, D; Canzian, F; Carracedo, A; Carter, BD; Castelao, JE; Chanock, SJ; Chatterjee, N; Chenevix-Trench, G; Clarke, CL; Couch, FJ; Cox, A; Cross, SS; Czene, K; Dai, JY; Earp, HS; Ekici, AB; Eliassen, AH; Eriksson, M; Evans, DG; Fasching, PA; Figueroa, J; Fritschi, L; Gabrielson, M; Gago-Dominguez, M; Gao, C; Gapstur, SM; Gaudet, MM; Giles, GG; González-Neira, A; Guénel, P; Haeberle, L; Haiman, CA; Håkansson, N; Hall, P; Hamann, U; Hatse, S; Heyworth, J; Holleczek, B; Hoover, RN; Hopper, JL; Howell, A; Hunter, DJ; ABCTB Investigators; kConFab/AOCS Investigators; John, EM; Jones, ME; Kaaks, R; Keeman, R; Kitahara, CM; Ko, Y-D; Koutros, S; Kurian, AW; Lambrechts, D; Marchand, LL; Lee, E; Lejbkowicz, F; Linet, M; Lissowska, J; Llaneza, A; MacInnis, RJ; Martinez, ME; Maurer, T; McLean, C; Neuhausen, SL; Newman, WG; Norman, A; O'Brien, KM; Olshan, AF; Olson, JE; Olsson, H; Orr, N; Perou, CM; Pita, G; Polley, EC; Prentice, RL; Rennert, G; Rennert, HS; Ruddy, KJ; Sandler, DP; Saunders, C; Schoemaker, MJ; Schöttker, B; Schumacher, F; Scott, C; Scott, RJ; Shu, X-O; Smeets, A; Southey, MC; Spinelli, JJ; Stone, J; Swerdlow, AJ; Tamimi, RM; Taylor, JA; Troester, MA; Vachon, CM; van Veen, EM; Wang, X; Weinberg, CR; Weltens, C; Willett, W; Winham, SJ; Wolk, A; Yang, XR; Zheng, W; Ziogas, A; Dunning, AM; Pharoah, PDP; Schmidt, MK; Kraft, P; Easton, DF; Milne, RL; García-Closas, M; Chang-Claude, J (2020-05-02)
      We evaluated the joint associations between a new 313-variant PRS (PRS313) and questionnaire-based breast cancer risk factors for women of European ancestry, using 72,284 cases and 80,354 controls from the Breast Cancer ...
    • Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation. 

      Ghoussaini, M; French, JD; Michailidou, K; Nord, S; Beesley, J; Canisus, S; Hillman, KM; Kaufmann, S; Sivakumaran, H; Moradi Marjaneh, M; Lee, JS; Dennis, J; Bolla, MK; Wang, Q; Dicks, E; Milne, RL; Hopper, JL; Southey, MC; Schmidt, MK; Broeks, A; Muir, K; Lophatananon, A; Fasching, PA; Beckmann, MW; Fletcher, O; Johnson, N; Sawyer, EJ; Tomlinson, I; Burwinkel, B; Marme, F; Guénel, P; Truong, T; Bojesen, SE; Flyger, H; Benitez, J; González-Neira, A; Alonso, MR; Pita, G; Neuhausen, SL; Anton-Culver, H; Brenner, H; Arndt, V; Meindl, A; Schmutzler, RK; Brauch, H; Hamann, U; Tessier, DC; Vincent, D; Nevanlinna, H; Khan, S; Matsuo, K; Ito, H; Dörk, T; Bogdanova, NV; Lindblom, A; Margolin, S; Mannermaa, A; Kosma, V-M; kConFab/AOCS Investigators; Wu, AH; Van Den Berg, D; Lambrechts, D; Floris, G; Chang-Claude, J; Rudolph, A; Radice, P; Barile, M; Couch, FJ; Hallberg, E; Giles, GG; Haiman, CA; Le Marchand, L; Goldberg, MS; Teo, SH; Yip, CH; Borresen-Dale, A-L; NBCS Collaborators; Zheng, W; Cai, Q; Winqvist, R; Pylkäs, K; Andrulis, IL; Devilee, P; Tollenaar, RAEM; García-Closas, M; Figueroa, J; Hall, P; Czene, K; Brand, JS; Darabi, H; Eriksson, M; Hooning, MJ; Koppert, LB; Li, J; Shu, X-O; Zheng, Y; Cox, A; Cross, SS; Shah, M; Rhenius, V; Choi, J-Y; Kang, D; Hartman, M; Chia, KS; Kabisch, M; Torres, D; Luccarini, C; Conroy, DM; Jakubowska, A; Lubinski, J; Sangrajrang, S; Brennan, P; Olswold, C; Slager, S; Shen, C-Y; Hou, M-F; Swerdlow, A; Schoemaker, MJ; Simard, J; Pharoah, PDP; Kristensen, V; Chenevix-Trench, G; Easton, DF; Dunning, AM; Edwards, SL (2016-10)
      Genome-wide association studies (GWASs) have revealed increased breast cancer risk associated with multiple genetic variants at 5p12. Here, we report the fine mapping of this locus using data from 104,660 subjects from 50 ...
    • Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus. 

      Horne, HN; Chung, CC; Zhang, H; Yu, K; Prokunina-Olsson, L; Michailidou, K; Bolla, MK; Wang, Q; Dennis, J; Hopper, JL; Southey, MC; Schmidt, MK; Broeks, A; Muir, K; Lophatananon, A; Fasching, PA; Beckmann, MW; Fletcher, O; Johnson, N; Sawyer, EJ; Tomlinson, I; Burwinkel, B; Marme, F; Guénel, P; Truong, T; Bojesen, SE; Flyger, H; Benitez, J; González-Neira, A; Anton-Culver, H; Neuhausen, SL; Brenner, H; Arndt, V; Meindl, A; Schmutzler, RK; Brauch, H; Hamann, U; Nevanlinna, H; Khan, S; Matsuo, K; Iwata, H; Dörk, T; Bogdanova, NV; Lindblom, A; Margolin, S; Mannermaa, A; Kosma, V-M; Chenevix-Trench, G; kConFab/AOCS Investigators; Wu, AH; Ven den Berg, D; Smeets, A; Zhao, H; Chang-Claude, J; Rudolph, A; Radice, P; Barile, M; Couch, FJ; Vachon, C; Giles, GG; Milne, RL; Haiman, CA; Marchand, LL; Goldberg, MS; Teo, SH; Taib, NAM; Kristensen, V; Borresen-Dale, A-L; Zheng, W; Shrubsole, M; Winqvist, R; Jukkola-Vuorinen, A; Andrulis, IL; Knight, JA; Devilee, P; Seynaeve, C; García-Closas, M; Czene, K; Darabi, H; Hollestelle, A; Martens, JWM; Li, J; Lu, W; Shu, X-O; Cox, A; Cross, SS; Blot, W; Cai, Q; Shah, M; Luccarini, C; Baynes, C; Harrington, P; Kang, D; Choi, J-Y; Hartman, M; Chia, KS; Kabisch, M; Torres, D; Jakubowska, A; Lubinski, J; Sangrajrang, S; Brennan, P; Slager, S; Yannoukakos, D; Shen, C-Y; Hou, M-F; Swerdlow, A; Orr, N; Simard, J; Hall, P; Pharoah, PDP; Easton, DF; Chanock, SJ; Dunning, AM; Figueroa, JD (2016-01)
      The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identified a single nucleotide polymorphism (SNP) rs11249433 at 1p11.2 associated with breast cancer risk. To fine-map this locus, ...
    • Genetic modifiers of CHEK2*1100delC-associated breast cancer risk. 

      Muranen, TA; Greco, D; Blomqvist, C; Aittomäki, K; Khan, S; Hogervorst, F; Verhoef, S; Pharoah, PDP; Dunning, AM; Shah, M; Luben, R; Bojesen, SE; Nordestgaard, BG; Schoemaker, M; Swerdlow, A; García-Closas, M; Figueroa, J; Dörk, T; Bogdanova, NV; Hall, P; Li, J; Khusnutdinova, E; Bermisheva, M; Kristensen, V; Borresen-Dale, A-L; NBCS Investigators; Peto, J; Dos Santos Silva, I; Couch, FJ; Olson, JE; Hillemans, P; Park-Simon, T-W; Brauch, H; Hamann, U; Burwinkel, B; Marme, F; Meindl, A; Schmutzler, RK; Cox, A; Cross, SS; Sawyer, EJ; Tomlinson, I; Lambrechts, D; Moisse, M; Lindblom, A; Margolin, S; Hollestelle, A; Martens, JWM; Fasching, PA; Beckmann, MW; Andrulis, IL; Knight, JA; kConFab/AOCS Investigators; Anton-Culver, H; Ziogas, A; Giles, GG; Milne, RL; Brenner, H; Arndt, V; Mannermaa, A; Kosma, V-M; Chang-Claude, J; Rudolph, A; Devilee, P; Seynaeve, C; Hopper, JL; Southey, MC; John, EM; Whittemore, AS; Bolla, MK; Wang, Q; Michailidou, K; Dennis, J; Easton, DF; Schmidt, MK; Nevanlinna, H (2017-05)
      Purpose CHEK2*1100delC is a founder variant in European populations that confers a two- to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk associated with ...
    • <i>PHIP</i> - a novel candidate breast cancer susceptibility locus on 6q14.1. 

      Jiao, X; Aravidis, C; Marikkannu, R; Rantala, J; Picelli, S; Adamovic, T; Liu, T; Maguire, P; Kremeyer, B; Luo, L; von Holst, S; Kontham, V; Thutkawkorapin, J; Margolin, S; Du, Q; Lundin, J; Michailidou, K; Bolla, MK; Wang, Q; Dennis, J; Lush, M; Ambrosone, CB; Andrulis, IL; Anton-Culver, H; Antonenkova, NN; Arndt, V; Beckmann, MW; Blomqvist, C; Blot, W; Boeckx, B; Bojesen, SE; Bonanni, B; Brand, JS; Brauch, H; Brenner, H; Broeks, A; Brüning, T; Burwinkel, B; Cai, Q; Chang-Claude, J; NBCS Collaborators; Couch, FJ; Cox, A; Cross, SS; Deming-Halverson, SL; Devilee, P; Dos-Santos-Silva, I; Dörk, T; Eriksson, M; Fasching, PA; Figueroa, J; Flesch-Janys, D; Flyger, H; Gabrielson, M; García-Closas, M; Giles, GG; González-Neira, A; Guénel, P; Guo, Q; Gündert, M; Haiman, CA; Hallberg, E; Hamann, U; Harrington, P; Hooning, MJ; Hopper, JL; Huang, G; Jakubowska, A; Jones, ME; Kerin, MJ; Kosma, V-M; Kristensen, VN; Lambrechts, D; Le Marchand, L; Lubinski, J; Mannermaa, A; Martens, JWM; Meindl, A; Milne, RL; Mulligan, AM; Neuhausen, SL; Nevanlinna, H; Peto, J; Pylkäs, K; Radice, P; Rhenius, V; Sawyer, EJ; Schmidt, MK; Schmutzler, RK; Seynaeve, C; Shah, M; Simard, J; Southey, MC; Swerdlow, AJ; Truong, T; Wendt, C; Winqvist, R; Zheng, W; kConFab/AOCS Investigators; Benitez, J; Dunning, AM; Pharoah, PDP; Easton, DF; Czene, K; Hall, P; Lindblom, A (2017-11)
      Most non-<i>BRCA1/2</i> breast cancer families have no identified genetic cause. We used linkage and haplotype analyses in familial and sporadic breast cancer cases to identify a susceptibility locus on chromosome 6q. Two ...
    • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. 

      Milne, RL; Kuchenbaecker, KB; Michailidou, K; Beesley, J; Kar, S; Lindström, S; Hui, S; Lemaçon, A; Soucy, P; Dennis, J; Jiang, X; Rostamianfar, A; Finucane, H; Bolla, MK; McGuffog, L; Wang, Q; Aalfs, CM; ABCTB Investigators; Adams, M; Adlard, J; Agata, S; Ahmed, S; Ahsan, H; Aittomäki, K; Al-Ejeh, F; Allen, J; Ambrosone, CB; Amos, CI; Andrulis, IL; Anton-Culver, H; Antonenkova, NN; Arndt, V; Arnold, N; Aronson, KJ; Auber, B; Auer, PL; Ausems, MGEM; Azzollini, J; Bacot, F; Balmaña, J; Barile, M; Barjhoux, L; Barkardottir, RB; Barrdahl, M; Barnes, D; Barrowdale, D; Baynes, C; Beckmann, MW; Benitez, J; Bermisheva, M; Bernstein, L; Bignon, Y-J; Blazer, KR; Blok, MJ; Blomqvist, C; Blot, W; Bobolis, K; Boeckx, B; Bogdanova, NV; Bojesen, A; Bojesen, SE; Bonanni, B; Børresen-Dale, A-L; Bozsik, A; Bradbury, AR; Brand, JS; Brauch, H; Brenner, H; Bressac-de Paillerets, B; Brewer, C; Brinton, L; Broberg, P; Brooks-Wilson, A; Brunet, J; Brüning, T; Burwinkel, B; Buys, SS; Byun, J; Cai, Q; Caldés, T; Caligo, MA; Campbell, I; Canzian, F; Caron, O; Carracedo, A; Carter, BD; Castelao, JE; Castera, L; Caux-Moncoutier, V; Chan, SB; Chang-Claude, J; Chanock, SJ; Chen, X; Cheng, T-YD; Chiquette, J; Christiansen, H; Claes, KBM; Clarke, CL; Conner, T; Conroy, DM; Cook, J; Cordina-Duverger, E; Cornelissen, S; Coupier, I; Cox, A; Cox, DG; Cross, SS; Cuk, K; Cunningham, JM; Czene, K; Daly, MB; Damiola, F; Darabi, H; Davidson, R; De Leeneer, K; Devilee, P; Dicks, E; Diez, O; Ding, YC; Ditsch, N; Doheny, KF; Domchek, SM; Dorfling, CM; Dörk, T; Dos-Santos-Silva, I; Dubois, S; Dugué, P-A; Dumont, M; Dunning, AM; Durcan, L; Dwek, M; Dworniczak, B; Eccles, D; Eeles, R; Ehrencrona, H; Eilber, U; Ejlertsen, B; Ekici, AB; Eliassen, AH; EMBRACE; Engel, C; Eriksson, M; Fachal, L; Faivre, L; Fasching, PA; Faust, U; Figueroa, J; Flesch-Janys, D; Fletcher, O; Flyger, H; Foulkes, WD; Friedman, E; Fritschi, L; Frost, D; Gabrielson, M; Gaddam, P; Gammon, MD; Ganz, PA; Gapstur, SM; Garber, J; Garcia-Barberan, V; García-Sáenz, JA; Gaudet, MM; Gauthier-Villars, M; Gehrig, A; GEMO Study Collaborators; Georgoulias, V; Gerdes, A-M; Giles, GG; Glendon, G; Godwin, AK; Goldberg, MS; Goldgar, DE; González-Neira, A; Goodfellow, P; Greene, MH; Alnæs, GIG; Grip, M; Gronwald, J; Grundy, A; Gschwantler-Kaulich, D; Guénel, P; Guo, Q; Haeberle, L; Hahnen, E; Haiman, CA; Håkansson, N; Hallberg, E; Hamann, U; Hamel, N; Hankinson, S; Hansen, TVO; Harrington, P; Hart, SN; Hartikainen, JM; Healey, CS; HEBON; Hein, A; Helbig, S; Henderson, A; Heyworth, J; Hicks, B; Hillemanns, P; Hodgson, S; Hogervorst, FB; Hollestelle, A; Hooning, MJ; Hoover, B; Hopper, JL; Hu, C; Huang, G; Hulick, PJ; Humphreys, K; Hunter, DJ; Imyanitov, EN; Isaacs, C; Iwasaki, M; Izatt, L; Jakubowska, A; James, P; Janavicius, R; Janni, W; Jensen, UB; John, EM; Johnson, N; Jones, K; Jones, M; Jukkola-Vuorinen, A; Kaaks, R; Kabisch, M; Kaczmarek, K; Kang, D; Kast, K; kConFab/AOCS Investigators; Keeman, R; Kerin, MJ; Kets, CM; Keupers, M; Khan, S; Khusnutdinova, E; Kiiski, JI; Kim, S-W; Knight, JA; Konstantopoulou, I; Kosma, V-M; Kristensen, VN; Kruse, TA; Kwong, A; Lænkholm, A-V; Laitman, Y; Lalloo, F; Lambrechts, D; Landsman, K; Lasset, C; Lazaro, C; Le Marchand, L; Lecarpentier, J; Lee, A; Lee, E; Lee, JW; Lee, MH; Lejbkowicz, F; Lesueur, F; Li, J; Lilyquist, J; Lincoln, A; Lindblom, A; Lissowska, J; Lo, W-Y; Loibl, S; Long, J; Loud, JT; Lubinski, J; Luccarini, C; Lush, M; MacInnis, RJ; Maishman, T; Makalic, E; Kostovska, IM; Malone, KE; Manoukian, S; Manson, JE; Margolin, S; Martens, JWM; Martinez, ME; Matsuo, K; Mavroudis, D; Mazoyer, S; McLean, C; Meijers-Heijboer, H; Menéndez, P; Meyer, J; Miao, H; Miller, A; Miller, N; Mitchell, G; Montagna, M; Muir, K; Mulligan, AM; Mulot, C; Nadesan, S; Nathanson, KL; NBSC Collaborators; Neuhausen, SL; Nevanlinna, H; Nevelsteen, I; Niederacher, D; Nielsen, SF; Nordestgaard, BG; Norman, A; Nussbaum, RL; Olah, E; Olopade, OI; Olson, JE; Olswold, C; Ong, K-R; Oosterwijk, JC; Orr, N; Osorio, A; Pankratz, VS; Papi, L; Park-Simon, T-W; Paulsson-Karlsson, Y; Lloyd, R; Pedersen, IS; Peissel, B; Peixoto, A; Perez, JIA; Peterlongo, P; Peto, J; Pfeiler, G; Phelan, CM; Pinchev, M; Plaseska-Karanfilska, D; Poppe, B; Porteous, ME; Prentice, R; Presneau, N; Prokofieva, D; Pugh, E; Pujana, MA; Pylkäs, K; Rack, B; Radice, P; Rahman, N; Rantala, J; Rappaport-Fuerhauser, C; Rennert, G; Rennert, HS; Rhenius, V; Rhiem, K; Richardson, A; Rodriguez, GC; Romero, A; Romm, J; Rookus, MA; Rudolph, A; Ruediger, T; Saloustros, E; Sanders, J; Sandler, DP; Sangrajrang, S; Sawyer, EJ; Schmidt, DF; Schoemaker, MJ; Schumacher, F; Schürmann, P; Schwentner, L; Scott, C; Scott, RJ; Seal, S; Senter, L; Seynaeve, C; Shah, M; Sharma, P; Shen, C-Y; Sheng, X; Shimelis, H; Shrubsole, MJ; Shu, X-O; Side, LE; Singer, CF; Sohn, C; Southey, MC; Spinelli, JJ; Spurdle, AB; Stegmaier, C; Stoppa-Lyonnet, D; Sukiennicki, G; Surowy, H; Sutter, C; Swerdlow, A; Szabo, CI; Tamimi, RM; Tan, YY; Taylor, JA; Tejada, M-I; Tengström, M; Teo, SH; Terry, MB; Tessier, DC; Teulé, A; Thöne, K; Thull, DL; Tibiletti, MG; Tihomirova, L; Tischkowitz, M; Toland, AE; Tollenaar, RAEM; Tomlinson, I; Tong, L; Torres, D; Tranchant, M; Truong, T; Tucker, K; Tung, N; Tyrer, J; Ulmer, H-U; Vachon, C; van Asperen, CJ; Van Den Berg, D; van den Ouweland, AMW; van Rensburg, EJ; Varesco, L; Varon-Mateeva, R; Vega, A; Viel, A; Vijai, J; Vincent, D; Vollenweider, J; Walker, L; Wang, Z; Wang-Gohrke, S; Wappenschmidt, B; Weinberg, CR; Weitzel, JN; Wendt, C; Wesseling, J; Whittemore, AS; Wijnen, JT; Willett, W; Winqvist, R; Wolk, A; Wu, AH; Xia, L; Yang, XR; Yannoukakos, D; Zaffaroni, D; Zheng, W; Zhu, B; Ziogas, A; Ziv, E; Zorn, KK; Gago-Dominguez, M; Mannermaa, A; Olsson, H; Teixeira, MR; Stone, J; Offit, K; Ottini, L; Park, SK; Thomassen, M; Hall, P; Meindl, A; Schmutzler, RK; Droit, A; Bader, GD; Pharoah, PDP; Couch, FJ; Easton, DF; Kraft, P; Chenevix-Trench, G; García-Closas, M; Schmidt, MK; Antoniou, AC; Simard, J (2017-12)
      Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease. We conducted a GWAS using 21,468 ER-negative ...
    • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. 

      Mavaddat, N; Michailidou, K; Dennis, J; Lush, M; Fachal, L; Lee, A; Tyrer, JP; Chen, T-H; Wang, Q; Bolla, MK; Yang, X; Adank, MA; Ahearn, T; Aittomäki, K; Allen, J; Andrulis, IL; Anton-Culver, H; Antonenkova, NN; Arndt, V; Aronson, KJ; Auer, PL; Auvinen, P; Barrdahl, M; Beane Freeman, LE; Beckmann, MW; Behrens, S; Benitez, J; Bermisheva, M; Bernstein, L; Blomqvist, C; Bogdanova, NV; Bojesen, SE; Bonanni, B; Børresen-Dale, A-L; Brauch, H; Bremer, M; Brenner, H; Brentnall, A; Brock, IW; Brooks-Wilson, A; Brucker, SY; Brüning, T; Burwinkel, B; Campa, D; Carter, BD; Castelao, JE; Chanock, SJ; Chlebowski, R; Christiansen, H; Clarke, CL; Collée, JM; Cordina-Duverger, E; Cornelissen, S; Couch, FJ; Cox, A; Cross, SS; Czene, K; Daly, MB; Devilee, P; Dörk, T; Dos-Santos-Silva, I; Dumont, M; Durcan, L; Dwek, M; Eccles, DM; Ekici, AB; Eliassen, AH; Ellberg, C; Engel, C; Eriksson, M; Evans, DG; Fasching, PA; Figueroa, J; Fletcher, O; Flyger, H; Försti, A; Fritschi, L; Gabrielson, M; Gago-Dominguez, M; Gapstur, SM; García-Sáenz, JA; Gaudet, MM; Georgoulias, V; Giles, GG; Gilyazova, IR; Glendon, G; Goldberg, MS; Goldgar, DE; González-Neira, A; Grenaker Alnæs, GI; Grip, M; Gronwald, J; Grundy, A; Guénel, P; Haeberle, L; Hahnen, E; Haiman, CA; Håkansson, N; Hamann, U; Hankinson, SE; Harkness, EF; Hart, SN; He, W; Hein, A; Heyworth, J; Hillemanns, P; Hollestelle, A; Hooning, MJ; Hoover, RN; Hopper, JL; Howell, A; Huang, G; Humphreys, K; Hunter, DJ; Jakimovska, M; Jakubowska, A; Janni, W; John, EM; Johnson, N; Jones, ME; Jukkola-Vuorinen, A; Jung, A; Kaaks, R; Kaczmarek, K; Kataja, V; Keeman, R; Kerin, MJ; Khusnutdinova, E; Kiiski, JI; Knight, JA; Ko, Y-D; Kosma, V-M; Koutros, S; Kristensen, VN; Krüger, U; Kühl, T; Lambrechts, D; Le Marchand, L; Lee, E; Lejbkowicz, F; Lilyquist, J; Lindblom, A; Lindström, S; Lissowska, J; Lo, W-Y; Loibl, S; Long, J; Lubiński, J; Lux, MP; MacInnis, RJ; Maishman, T; Makalic, E; Maleva Kostovska, I; Mannermaa, A; Manoukian, S; Margolin, S; Martens, JWM; Martinez, ME; Mavroudis, D; McLean, C; Meindl, A; Menon, U; Middha, P; Miller, N; Moreno, F; Mulligan, AM; Mulot, C; Muñoz-Garzon, VM; Neuhausen, SL; Nevanlinna, H; Neven, P; Newman, WG; Nielsen, SF; Nordestgaard, BG; Norman, A; Offit, K; Olson, JE; Olsson, H; Orr, N; Pankratz, VS; Park-Simon, T-W; Perez, JIA; Pérez-Barrios, C; Peterlongo, P; Peto, J; Pinchev, M; Plaseska-Karanfilska, D; Polley, EC; Prentice, R; Presneau, N; Prokofyeva, D; Purrington, K; Pylkäs, K; Rack, B; Radice, P; Rau-Murthy, R; Rennert, G; Rennert, HS; Rhenius, V; Robson, M; Romero, A; Ruddy, KJ; Ruebner, M; Saloustros, E; Sandler, DP; Sawyer, EJ; Schmidt, DF; Schmutzler, RK; Schneeweiss, A; Schoemaker, MJ; Schumacher, F; Schürmann, P; Schwentner, L; Scott, C; Scott, RJ; Seynaeve, C; Shah, M; Sherman, ME; Shrubsole, MJ; Shu, X-O; Slager, S; Smeets, A; Sohn, C; Soucy, P; Southey, MC; Spinelli, JJ; Stegmaier, C; Stone, J; Swerdlow, AJ; Tamimi, RM; Tapper, WJ; Taylor, JA; Terry, MB; Thöne, K; Tollenaar, RAEM; Tomlinson, I; Truong, T; Tzardi, M; Ulmer, H-U; Untch, M; Vachon, CM; van Veen, EM; Vijai, J; Weinberg, CR; Wendt, C; Whittemore, AS; Wildiers, H; Willett, W; Winqvist, R; Wolk, A; Yang, XR; Yannoukakos, D; Zhang, Y; Zheng, W; Ziogas, A; ABCTB Investigators; kConFab/AOCS Investigators; NBCS Collaborators; Dunning, AM; Thompson, DJ; Chenevix-Trench, G; Chang-Claude, J; Schmidt, MK; Hall, P; Milne, RL; Pharoah, PDP; Antoniou, AC; Chatterjee, N; Kraft, P; García-Closas, M; Simard, J; Easton, DF (2019-01)
      Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen ...
    • RAD51B in Familial Breast Cancer. 

      Pelttari, LM; Khan, S; Vuorela, M; Kiiski, JI; Vilske, S; Nevanlinna, V; Ranta, S; Schleutker, J; Winqvist, R; Kallioniemi, A; Dörk, T; Bogdanova, NV; Figueroa, J; Pharoah, PDP; Schmidt, MK; Dunning, AM; García-Closas, M; Bolla, MK; Dennis, J; Michailidou, K; Wang, Q; Hopper, JL; Southey, MC; Rosenberg, EH; Fasching, PA; Beckmann, MW; Peto, J; Dos-Santos-Silva, I; Sawyer, EJ; Tomlinson, I; Burwinkel, B; Surowy, H; Guénel, P; Truong, T; Bojesen, SE; Nordestgaard, BG; Benitez, J; González-Neira, A; Neuhausen, SL; Anton-Culver, H; Brenner, H; Arndt, V; Meindl, A; Schmutzler, RK; Brauch, H; Brüning, T; Lindblom, A; Margolin, S; Mannermaa, A; Hartikainen, JM; Chenevix-Trench, G; kConFab/AOCS Investigators; Van Dyck, L; Janssen, H; Chang-Claude, J; Rudolph, A; Radice, P; Peterlongo, P; Hallberg, E; Olson, JE; Giles, GG; Milne, RL; Haiman, CA; Schumacher, F; Simard, J; Dumont, M; Kristensen, V; Borresen-Dale, A-L; Zheng, W; Beeghly-Fadiel, A; Grip, M; Andrulis, IL; Glendon, G; Devilee, P; Seynaeve, C; Hooning, MJ; Collée, M; Cox, A; Cross, SS; Shah, M; Luben, RN; Hamann, U; Torres, D; Jakubowska, A; Lubinski, J; Couch, FJ; Yannoukakos, D; Orr, N; Swerdlow, A; Darabi, H; Li, J; Czene, K; Hall, P; Easton, DF; Mattson, J; Blomqvist, C; Aittomäki, K; Nevanlinna, H (2016-01)
      Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study ...