Now showing items 1-3 of 3

    • Actin-myosin-based contraction is responsible for apoptotic nuclear disintegration. 

      Croft, DR; Coleman, ML; Li, S; Robertson, D; Sullivan, T; Stewart, CL; Olson, MF (2005-01-17)
      Membrane blebbing during the apoptotic execution phase results from caspase-mediated cleavage and activation of ROCK I. Here, we show that ROCK activity, myosin light chain (MLC) phosphorylation, MLC ATPase activity, and ...
    • Myosin and Actin Filaments in Muscle: Structures and Interactions. 

      Squire, JM; Paul, DM; Morris, EP (2017)
      In the last decade, improvements in electron microscopy and image processing have permitted significantly higher resolutions to be achieved (sometimes <1 nm) when studying isolated actin and myosin filaments. In the case ...
    • The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles. 

      Orme, MH; Liccardi, G; Moderau, N; Feltham, R; Wicky-John, S; Tenev, T; Aram, L; Wilson, R; Bianchi, K; Morris, O; Monteiro Domingues, C; Robertson, D; Tare, M; Wepf, A; Williams, D; Bergmann, A; Gstaiger, M; Arama, E; Ribeiro, PS; Meier, P (2016-01)
      Caspases provide vital links in non-apoptotic regulatory networks controlling inflammation, compensatory proliferation, morphology and cell migration. How caspases are activated under non-apoptotic conditions and process ...