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    • Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface. 

      Tang, H; Leung, L; Saturno, G; Viros, A; Smith, D; Di Leva, G; Morrison, E; Niculescu-Duvaz, D; Lopes, F; Johnson, L; Dhomen, N; Springer, C; Marais, R (2017-04-18)
      Lysyl oxidase (LOX) remodels the tumour microenvironment by cross-linking the extracellular matrix. LOX overexpression is associated with poor cancer outcomes. Here, we find that LOX regulates the epidermal growth factor ...