Now showing items 1-2 of 2

    • The Borg family of Cdc42 effector proteins Cdc42EP1-5. 

      Farrugia, AJ; Calvo, F (2016-12-15)
      Despite being discovered more than 15 years ago, the Borg (binder of Rho GTPases) family of Cdc42 effector proteins (Cdc42EP1-5) remains largely uncharacterised and relatively little is known about their structure, regulation ...
    • Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts. 

      Farrugia, AJ; Calvo, F (2017-01-02)
      Rho family GTPases such as Cdc42 are key regulators of essential cellular processes through their effects on cytoskeletal dynamics, signaling and gene expression. Rho GTPases modulate these functions by engaging a wide ...