Browsing by subject "Ribosomal Protein S6 Kinases, 90-kDa"
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The discovery of potent ribosomal S6 kinase inhibitors by high-throughput screening and structure-guided drug design. (2013-10)The ribosomal P70 S6 kinases play a crucial role in PI3K/mTOR regulated signalling pathways and are therefore potential targets for the treatment of a variety of diseases including diabetes and cancer. In this study we ...