Browsing by subject "p53-dependent g(1) arrest cell-cycle checkpoints synthetic lethal interactions invasive bladder-cancer retinoblastoma protein ionizing-radiation gamma-irradiation tumor suppression chk1 inhibitors repair pathways"
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Mechanism-Based Screen Establishes Signalling Framework for DNA Damage-Associated G1 Checkpoint Response (2012-02)DNA damage activates checkpoint controls which block progression of cells through the division cycle. Several different checkpoints exist that control transit at different positions in the cell cycle. A role for checkpoint ...