Now showing items 1-2 of 2

    • Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma. 

      Qin, EY; Cooper, DD; Abbott, KL; Lennon, J; Nagaraja, S; Mackay, A; Jones, C; Vogel, H; Jackson, PK; Monje, M (2017-08-24)
      The lateral ventricle subventricular zone (SVZ) is a frequent and consequential site of pediatric and adult glioma spread, but the cellular and molecular mechanisms mediating this are poorly understood. We demonstrate that ...
    • RHO binding to FAM65A regulates Golgi reorientation during cell migration. 

      Mardakheh, FK; Self, A; Marshall, CJ (2016-12-15)
      Directional cell migration involves reorientation of the secretory machinery. However, the molecular mechanisms that control this reorientation are not well characterised. Here, we identify a new Rho effector protein, named ...