Browsing ICR Divisions by author "Pandher, Rupinder Kaur"

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Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers: Preclinical Discovery to Phase I Trial Evaluation.

Ang, JE; Pandher, R; Ang, JC; Asad, YJ; Henley, AT; Valenti, M; Box, G; de Haven Brandon, A; Baird, RD; Friedman, L; Derynck, M; Vanhaesebroeck, B; Eccles, SA; Kaye, SB; Workman, P; de Bono, JS; Raynaud, FI (2016-06)

PI3K plays a key role in cellular metabolism and cancer. Using a mass spectrometry-based metabolomics platform, we discovered that plasma concentrations of 26 metabolites, including amino acids, acylcarnitines, and ...

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