Now showing items 1-4 of 4

    • CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus 

      Bernard, D; Martinez-Leal, JF; Rizzo, S; Martinez, D; Hudson, D; Visakorpi, T; Peters, G; Carnero, A; Beach, D; Gil, J (NATURE PUBLISHING GROUP, 2005-08-25)
      Control of cell proliferation by Polycomb group proteins (PcG) is an important facet of cellular homeostasis and its disruption can promote tumorigenesis. We recently described CBX7 as a novel PcG protein controlling the ...
    • Epithelial stem cells in human prostate growth and disease 

      Hudson, DL (NATURE PUBLISHING GROUP, 2004-09)
      Benign prostatic hyperplasia and prostate cancer arise as a consequence of changes in the balance between cell division and differentiation. Little, however, is known about the control of this process. Stem cells are a ...
    • The methyl-CpG- binding protein MECP2 is required for prostate cancer cell growth 

      Bernard, D; Gil, J; Dumont, P; Rizzo, S; Monte, D; Quatannens, B; Hudson, D; Visakorpi, T; Fuks, F; de Launoit, Y (NATURE PUBLISHING GROUP, 2006-03-02)
      The incidence of prostate cancer is increasing in western countries because of population aging. Prostate cancer begins as an androgen-dependent disease, but it can become androgen independent at a later stage or in tumors ...
    • Prostate epithelial stem cell culture 

      Hudson, DL (KLUWER ACADEMIC PUBL, 2003)
      The prostate gland is the site of the second most common cancer in men in the UK, with 9,280 deaths recorded in 2000. Another common disease of the prostate is benign prostatic hyperplasia and both conditions are believed ...