Now showing items 1-4 of 4

    • Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study. 

      Rambau, PF; Vierkant, RA; Intermaggio, MP; Kelemen, LE; Goodman, MT; Herpel, E; Pharoah, PD; Kommoss, S; Jimenez-Linan, M; Karlan, BY; Gentry-Maharaj, A; Menon, U; Polo, SH; Candido Dos Reis, FJ; Doherty, JA; Gayther, SA; Sharma, R; Larson, MC; Harnett, PR; Hatfield, E; de Andrade, JM; Nelson, GS; Steed, H; Schildkraut, JM; Carney, ME; Høgdall, E; Whittemore, AS; Widschwendter, M; Kennedy, CJ; Wang, F; Wang, Q; Wang, C; Armasu, SM; Daley, F; Coulson, P; Jones, ME; Anglesio, MS; Chow, C; de Fazio, A; García-Closas, M; Brucker, SY; Cybulski, C; Harris, HR; Hartkopf, AD; Huzarski, T; Jensen, A; Lubiński, J; Oszurek, O; Benitez, J; Mina, F; Staebler, A; Taran, FA; Pasternak, J; Talhouk, A; Rossing, MA; Hendley, J; AOCS Group; Edwards, RP; Fereday, S; Modugno, F; Ness, RB; Sieh, W; El-Bahrawy, MA; Winham, SJ; Lester, J; Kjaer, SK; Gronwald, J; Sinn, P; Fasching, PA; Chang-Claude, J; Moysich, KB; Bowtell, DD; Hernandez, BY; Luk, H; Behrens, S; Shah, M; Jung, A; Ghatage, P; Alsop, J; Alsop, K; García-Donas, J; Thompson, PJ; Swerdlow, AJ; Karpinskyj, C; Cazorla-Jiménez, A; García, MJ; Deen, S; Wilkens, LR; Palacios, J; Berchuck, A; Koziak, JM; Brenton, JD; Cook, LS; Goode, EL; Huntsman, DG; Ramus, SJ; Köbel, M (2018-10)
      We aimed to validate the prognostic association of p16 expression in ovarian high-grade serous carcinomas (HGSC) and to explore it in other ovarian carcinoma histotypes. p16 protein expression was assessed by clinical-grade ...
    • Ovarian Cancer Risk Factors by Histologic Subtype: An Analysis From the Ovarian Cancer Cohort Consortium. 

      Wentzensen, N; Poole, EM; Trabert, B; White, E; Arslan, AA; Patel, AV; Setiawan, VW; Visvanathan, K; Weiderpass, E; Adami, H-O; Black, A; Bernstein, L; Brinton, LA; Buring, J; Butler, LM; Chamosa, S; Clendenen, TV; Dossus, L; Fortner, R; Gapstur, SM; Gaudet, MM; Gram, IT; Hartge, P; Hoffman-Bolton, J; Idahl, A; Jones, M; Kaaks, R; Kirsh, V; Koh, W-P; Lacey, JV; Lee, I-M; Lundin, E; Merritt, MA; Onland-Moret, NC; Peters, U; Poynter, JN; Rinaldi, S; Robien, K; Rohan, T; Sandler, DP; Schairer, C; Schouten, LJ; Sjöholm, LK; Sieri, S; Swerdlow, A; Tjonneland, A; Travis, R; Trichopoulou, A; van den Brandt, PA; Wilkens, L; Wolk, A; Yang, HP; Zeleniuch-Jacquotte, A; Tworoger, SS (2016-08)
      <h4>Purpose</h4>An understanding of the etiologic heterogeneity of ovarian cancer is important for improving prevention, early detection, and therapeutic approaches. We evaluated 14 hormonal, reproductive, and lifestyle ...
    • Prognostic gene expression signature for high-grade serous ovarian cancer. 

      Millstein, J; Budden, T; Goode, EL; Anglesio, MS; Talhouk, A; Intermaggio, MP; Leong, HS; Chen, S; Elatre, W; Gilks, B; Nazeran, T; Volchek, M; Bentley, RC; Wang, C; Chiu, DS; Kommoss, S; Leung, SCY; Senz, J; Lum, A; Chow, V; Sudderuddin, H; Mackenzie, R; George, J; AOCS Group; Fereday, S; Hendley, J; Traficante, N; Steed, H; Koziak, JM; Köbel, M; McNeish, IA; Goranova, T; Ennis, D; Macintyre, G; Silva De Silva, D; Ramón Y Cajal, T; García-Donas, J; Hernando Polo, S; Rodriguez, GC; Cushing-Haugen, KL; Harris, HR; Greene, CS; Zelaya, RA; Behrens, S; Fortner, RT; Sinn, P; Herpel, E; Lester, J; Lubiński, J; Oszurek, O; Tołoczko, A; Cybulski, C; Menkiszak, J; Pearce, CL; Pike, MC; Tseng, C; Alsop, J; Rhenius, V; Song, H; Jimenez-Linan, M; Piskorz, AM; Gentry-Maharaj, A; Karpinskyj, C; Widschwendter, M; Singh, N; Kennedy, CJ; Sharma, R; Harnett, PR; Gao, B; Johnatty, SE; Sayer, R; Boros, J; Winham, SJ; Keeney, GL; Kaufmann, SH; Larson, MC; Luk, H; Hernandez, BY; Thompson, PJ; Wilkens, LR; Carney, ME; Trabert, B; Lissowska, J; Brinton, L; Sherman, ME; Bodelon, C; Hinsley, S; Lewsley, LA; Glasspool, R; Banerjee, SN; Stronach, EA; Haluska, P; Ray-Coquard, I; Mahner, S; Winterhoff, B; Slamon, D; Levine, DA; Kelemen, LE; Benitez, J; Chang-Claude, J; Gronwald, J; Wu, AH; Menon, U; Goodman, MT; Schildkraut, JM; Wentzensen, N; Brown, R; Berchuck, A; Chenevix-Trench, G; deFazio, A; Gayther, SA; García, MJ; Henderson, MJ; Rossing, MA; Beeghly-Fadiel, A; Fasching, PA; Orsulic, S; Karlan, BY; Konecny, GE; Huntsman, DG; Bowtell, DD; Brenton, JD; Doherty, JA; Pharoah, PDP; Ramus, SJ (2020-09)
      <h4>Background</h4>Median overall survival (OS) for women with high-grade serous ovarian cancer (HGSOC) is ∼4 years, yet survival varies widely between patients. There are no well-established, gene expression signatures ...
    • Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer. 

      Heindl, A; Lan, C; Rodrigues, DN; Koelble, K; Yuan, Y (2016-11)
      The tumor microenvironment is pivotal in influencing cancer progression and metastasis. Different cells co-exist with high spatial diversity within a patient, yet their combinatorial effects are poorly understood. We ...