Browsing ICR Divisions by subject "PRIMARY CUTANEOUS MELANOMA TUMOR-SUPPRESSOR GENE METASTATIC MELANOMA CELL-MIGRATION CANCER CELLS ACTIVATION SENESCENCE EXPRESSION PROLIFERATION INVASION"
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A caveolin-dependent and PI3K/AKT-independent role of PTEN in beta-catenin transcriptional activity (2015-08)Loss of the tumour suppressor PTEN is frequent in human melanoma, results in MAPK activation, suppresses senescence and mediates metastatic behaviour. How PTEN loss mediates these effects is unknown. Here we show that loss ...