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    • Embracing model-based designs for dose-finding trials. 

      Love, SB; Brown, S; Weir, CJ; Harbron, C; Yap, C; Gaschler-Markefski, B; Matcham, J; Caffrey, L; McKevitt, C; Clive, S; Craddock, C; Spicer, J; Cornelius, V (2017-07)
      BACKGROUND:Dose-finding trials are essential to drug development as they establish recommended doses for later-phase testing. We aim to motivate wider use of model-based designs for dose finding, such as the continual ...