Now showing items 1-2 of 2

    • Isolated limb perfusion with biochemotherapy and oncolytic virotherapy combines with radiotherapy and surgery to overcome treatment resistance in an animal model of extremity soft tissue sarcoma. 

      Wilkinson, MJ; Smith, HG; Pencavel, TD; Mansfield, DC; Kyula-Currie, J; Khan, AA; McEntee, G; Roulstone, V; Hayes, AJ; Harrington, KJ (2016-09)
      The management of locally advanced or recurrent extremity sarcoma often necessitates multimodal therapy to preserve a limb, of which isolated limb perfusion (ILP) is a key component. However, with standard chemotherapeutic ...
    • Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes. 

      Tubio, JMC; Li, Y; Ju, YS; Martincorena, I; Cooke, SL; Tojo, M; Gundem, G; Pipinikas, CP; Zamora, J; Raine, K; Menzies, A; Roman-Garcia, P; Fullam, A; Gerstung, M; Shlien, A; Tarpey, PS; Papaemmanuil, E; Knappskog, S; Van Loo, P; Ramakrishna, M; Davies, HR; Marshall, J; Wedge, DC; Teague, JW; Butler, AP; Nik-Zainal, S; Alexandrov, L; Behjati, S; Yates, LR; Bolli, N; Mudie, L; Hardy, C; Martin, S; McLaren, S; O'Meara, S; Anderson, E; Maddison, M; Gamble, S; Foster, C; Warren, AY; Whitaker, H; Brewer, D; Eeles, R; Cooper, C; Neal, D; Lynch, AG; Visakorpi, T; Isaacs, WB; Veer, LV; Caldas, C; Desmedt, C; Sotiriou, C; Aparicio, S; Foekens, JA; Eyfjörd, JE; Lakhani, SR; Thomas, G; Myklebost, O; Span, PN; Børresen-Dale, A-L; Richardson, AL; Van de Vijver, M; Vincent-Salomon, A; Van den Eynden, GG; Flanagan, AM; Futreal, PA; Janes, SM; Bova, GS; Stratton, MR; McDermott, U; Campbell, PJ; ICGC Breast Cancer Group; ICGC Bone Cancer Group; ICGC Prostate Cancer Group (2014-08)
      Long interspersed nuclear element-1 (L1) retrotransposons are mobile repetitive elements that are abundant in the human genome. L1 elements propagate through RNA intermediates. In the germ line, neighboring, nonrepetitive ...