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    • Persistent DNA strand breaks induce a CAF-like phenotype in normal fibroblasts. 

      Legrand, AJ; Poletto, M; Pankova, D; Clementi, E; Moore, J; Castro-Giner, F; Ryan, AJ; O'Neill, E; Markkanen, E; Dianov, GL (2018-03-02)
      Cancer-associated fibroblasts (CAFs) are an emerging target for cancer therapy as they promote tumour growth and metastatic potential. However, CAF targeting is complicated by the lack of knowledge-based strategies aiming ...