Browsing ICR Divisions by subject "transcriptional silencing"
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Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability. (2019-01-17)Cohesin subunits are frequently mutated in cancer, but how they function as tumor suppressors is unknown. Cohesin mediates sister chromatid cohesion, but this is not always perturbed in cancer cells. Here, we identify a ...