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dc.contributor.authorGupta, Aen_US
dc.contributor.authorAnjomani-Virmouni, Sen_US
dc.contributor.authorKoundouros, Nen_US
dc.contributor.authorPoulogiannis, Gen_US
dc.date.accessioned2018-01-24T15:39:46Z
dc.date.issued2017-01en_US
dc.identifier.citationMolecular & cellular oncology, 2017, 4 (6), pp. e1329692 - ?en_US
dc.identifier.issn2372-3556en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/1025
dc.identifier.eissn2372-3556en_US
dc.identifier.doi10.1080/23723556.2017.1329692en_US
dc.description.abstractCancer and Parkinson disease (PD) derive from distinct alterations in cellular processes, yet there are pathogenic mutations that are unequivocally linked to both diseases. Here we expand on our recent findings that loss of parkin RBR E3 ubiquitin protein ligase (PRKN, best known as PARK2)-which is genetically linked to PD-promotes cancer progression via redox-mediated inactivation of phosphatase and tensin homolog (PTEN) by S-nitrosylation.en_US
dc.formatElectronic-eCollectionen_US
dc.format.extente1329692 - ?en_US
dc.languageengen_US
dc.language.isoengen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.titlePARK2 loss promotes cancer progression via redox-mediated inactivation of PTEN.en_US
dc.typeJournal Article
dcterms.dateAccepted2017-05-09en_US
rioxxterms.versionofrecord10.1080/23723556.2017.1329692en_US
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0en_US
rioxxterms.licenseref.startdate2017-01en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfMolecular & cellular oncologyen_US
pubs.issue6en_US
pubs.notesNo embargoen_US
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Biology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Biology/Signalling & Cancer Metabolism
pubs.publication-statusPublisheden_US
pubs.volume4en_US
pubs.embargo.termsNo embargoen_US
icr.researchteamSignalling & Cancer Metabolismen_US
dc.contributor.icrauthorPoulogiannis, Georgiosen_US


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