dc.contributor.author | Kouijzer, IJE | |
dc.contributor.author | Scheper, H | |
dc.contributor.author | de Rooy, JWJ | |
dc.contributor.author | Bloem, JL | |
dc.contributor.author | Janssen, MJR | |
dc.contributor.author | van den Hoven, L | |
dc.contributor.author | Hosman, AJF | |
dc.contributor.author | Visser, LG | |
dc.contributor.author | Oyen, WJG | |
dc.contributor.author | Bleeker-Rovers, CP | |
dc.contributor.author | de Geus-Oei, L-F | |
dc.date.accessioned | 2018-01-26T09:34:35Z | |
dc.date.issued | 2018-05 | |
dc.identifier.citation | European journal of nuclear medicine and molecular imaging, 2018, 45 (5), pp. 798 - 805 | |
dc.identifier.issn | 1619-7070 | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/1031 | |
dc.identifier.eissn | 1619-7089 | |
dc.identifier.doi | 10.1007/s00259-017-3912-0 | |
dc.description.abstract | PURPOSE:The aim of this study was to determine the diagnostic value of 18F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT) and magnetic resonance imaging (MRI) in diagnosing vertebral osteomyelitis. METHODS:From November 2015 until December 2016, 32 patients with suspected vertebral osteomyelitis were prospectively included. All patients underwent both 18F-FDG-PET/CT and MRI within 48 h. All images were independently reevaluated by two radiologists and two nuclear medicine physicians who were blinded to each others' image interpretation. 18F-FDG-PET/CT and MRI were compared to the clinical diagnosis according to international guidelines. RESULTS:For 18F-FDG-PET/CT, sensitivity, specificity, PPV, and NPV in diagnosing vertebral osteomyelitis were 100%, 83.3%, 90.9%, and 100%, respectively. For MRI, sensitivity, specificity, PPV, and NPV were 100%, 91.7%, 95.2%, and 100%, respectively. MRI detected more epidural/spinal abscesses. An important advantage of 18F-FDG-PET/CT is the detection of metastatic infection (16 patients, 50.0%). CONCLUSION:18F-FDG-PET/CT and MRI are both necessary techniques in diagnosing vertebral osteomyelitis. An important advantage of 18F-FDG-PET/CT is the visualization of metastatic infection, especially in patients with bacteremia. MRI is more sensitive in detection of small epidural abscesses. | |
dc.format | Print-Electronic | |
dc.format.extent | 798 - 805 | |
dc.language | eng | |
dc.language.iso | eng | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | |
dc.subject | Spine | |
dc.subject | Humans | |
dc.subject | Osteomyelitis | |
dc.subject | Fluorodeoxyglucose F18 | |
dc.subject | Radiopharmaceuticals | |
dc.subject | Positron-Emission Tomography | |
dc.subject | Tomography, X-Ray Computed | |
dc.subject | Magnetic Resonance Imaging | |
dc.subject | Sensitivity and Specificity | |
dc.subject | Prospective Studies | |
dc.subject | Adult | |
dc.subject | Aged | |
dc.subject | Aged, 80 and over | |
dc.subject | Middle Aged | |
dc.subject | Female | |
dc.subject | Male | |
dc.subject | Positron Emission Tomography Computed Tomography | |
dc.title | The diagnostic value of 18F-FDG-PET/CT and MRI in suspected vertebral osteomyelitis - a prospective study. | |
dc.type | Journal Article | |
dcterms.dateAccepted | 2017-12-10 | |
rioxxterms.versionofrecord | 10.1007/s00259-017-3912-0 | |
rioxxterms.licenseref.uri | https://creativecommons.org/licenses/by/4.0 | |
rioxxterms.licenseref.startdate | 2018-05 | |
rioxxterms.type | Journal Article/Review | |
dc.relation.isPartOf | European journal of nuclear medicine and molecular imaging | |
pubs.issue | 5 | |
pubs.notes | Not known | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Molecular Imaging | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Molecular Imaging | |
pubs.publication-status | Published | |
pubs.volume | 45 | |
pubs.embargo.terms | Not known | |
icr.researchteam | Translational Molecular Imaging | en_US |
dc.contributor.icrauthor | Oyen, Willem | |