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The management of soft tissue tumours of the abdominal wall.

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Publication Date
2017-09
ICR Author
Hayes, Andrew
Smith, Henry
Messiou, Christina
Marsden,
Author
Smith, HG
Tzanis, D
Messiou, C
Benson, C
van der Hage, JA
Fiore, M
Bonvalot, S
Hayes, AJ
Type
Journal Article
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Abstract
BACKGROUND: Soft tissue tumours of the abdominal wall account for approximately 10% of all soft tissue tumours. Tumours at this site comprise a heterogeneous group of pathologies with distinct clinical behaviours and responses to treatment. The management of these tumours has largely been extrapolated from studies of soft tissue tumours at other sites. This review aims to summarise the existing data relating to abdominal wall tumours and suggest principles for managing soft tissue tumours at this site. METHODS: Relevant articles were retrieved from a comprehensive literature search using the PubMed database. Key words included abdominal wall, soft tissue tumours, surgery, radiotherapy and chemotherapy. No restrictions on publication date were used. RESULTS: The most common pathologies presenting in the abdominal wall are desmoid tumours, soft-tissue sarcoma and dermatofibrosarcoma protuberans (DFSP). Desmoid tumours should be managed with an initial period of observation, with surgery reserved for progressive lesions. Surgery should be the primary treatment for soft-tissue sarcomas and DFSP, with radiotherapy reserved for large-high grade tumours and preferentially given pre-operatively. CONCLUSIONS: Abdominal wall tumours are rare and should be managed in centres with experience in the management of soft tissue tumours. Management should be tailored to the biological behaviour of specific pathologies.
URL
https://repository.icr.ac.uk/handle/internal/1135
Collections
  • Radiotherapy and Imaging
Version of record
10.1016/j.ejso.2017.04.009
Subject
Abdominal wall
Dermatofibrosarcoma protuberans
Desmoid tumours
Soft tissue sarcoma
Abdominal Wall
Dermatofibrosarcoma
Fibromatosis, Abdominal
Humans
Neoplasm Staging
Reconstructive Surgical Procedures
Sarcoma
Soft Tissue Neoplasms
Research team
Sarcoma and Melanoma Surgery
Language
eng
Date accepted
2017-04-24
License start date
2017-09
Citation
Eur J Surg Oncol, 2017, 43 (9), pp. 1647 - 1655

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