Oesophageal cancer.

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Date
2017-11Author
Lagergren, J
Smyth, E
Cunningham, D
Lagergren, P
Type
Journal Article
Metadata
Show full item recordAbstract
Oesophageal cancer is a clinically challenging disease that requires a multidisciplinary approach. Extensive treatment might be associated with a considerable decline in health-related quality of life and yet still a poor prognosis. In recent decades, prognosis has gradually improved in many countries. Endoscopic procedures have increasingly been used in the treatment of premalignant and early oesophageal tumours. Neoadjuvant therapy with chemotherapy or chemoradiotherapy has supplemented surgery as standard treatment of locally advanced oesophageal cancer. Surgery has become more standardised and centralised. Several therapeutic alternatives are available for palliative treatment. This Seminar aims to provide insights into the current clinical management, ongoing controversies, and future needs in oesophageal cancer.
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Subject
Humans
Adenocarcinoma
Carcinoma, Squamous Cell
Esophageal Neoplasms
Esophagoscopy
Prognosis
Disease-Free Survival
Combined Modality Therapy
Esophagectomy
Risk Assessment
Survival Analysis
Quality of Life
Aged
Aged, 80 and over
Middle Aged
Female
Male
Chemoradiotherapy, Adjuvant
Research team
Medicine (RMH Smith Cunningham)
Language
eng
Date accepted
2017-04-13
License start date
2017-11
Citation
Lancet (London, England), 2017, 390 (10110), pp. 2383 - 2396