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dc.contributor.authorTang, SS-K
dc.contributor.authorKaptanis, S
dc.contributor.authorHaddow, JB
dc.contributor.authorMondani, G
dc.contributor.authorElsberger, B
dc.contributor.authorTasoulis, MK
dc.contributor.authorObondo, C
dc.contributor.authorJohns, N
dc.contributor.authorIsmail, W
dc.contributor.authorSyed, A
dc.contributor.authorKissias, P
dc.contributor.authorVenn, M
dc.contributor.authorSundaramoorthy, S
dc.contributor.authorIrwin, G
dc.contributor.authorSami, AS
dc.contributor.authorElfadl, D
dc.contributor.authorBaggaley, A
dc.contributor.authorRemoundos, DD
dc.contributor.authorLanglands, F
dc.contributor.authorCharalampoudis, P
dc.contributor.authorBarber, Z
dc.contributor.authorHamilton-Burke, WLS
dc.contributor.authorKhan, A
dc.contributor.authorSirianni, C
dc.contributor.authorMerker, LA-MG
dc.contributor.authorSaha, S
dc.contributor.authorLane, RA
dc.contributor.authorChopra, S
dc.contributor.authorDupré, S
dc.contributor.authorManning, AT
dc.contributor.authorSt John, ER
dc.contributor.authorMusbahi, A
dc.contributor.authorDlamini, N
dc.contributor.authorMcArdle, CL
dc.contributor.authorWright, C
dc.contributor.authorMurphy, JO
dc.contributor.authorAggarwal, R
dc.contributor.authorDordea, M
dc.contributor.authorBosch, K
dc.contributor.authorEgbeare, D
dc.contributor.authorOsman, H
dc.contributor.authorTayeh, S
dc.contributor.authorRazi, F
dc.contributor.authorIqbal, J
dc.contributor.authorLedwidge, SFC
dc.contributor.authorAlbert, V
dc.contributor.authorMasannat, Y
dc.date.accessioned2018-02-20T12:06:44Z
dc.date.issued2017-10
dc.identifier.citationEuropean journal of cancer (Oxford, England : 1990), 2017, 84 pp. 315 - 324
dc.identifier.issn0959-8049
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/1403
dc.identifier.eissn1879-0852
dc.identifier.doi10.1016/j.ejca.2017.07.032
dc.description.abstractIntroduction There is variation in margin policy for breast conserving therapy (BCT) in the UK and Ireland. In response to the Society of Surgical Oncology and American Society for Radiation Oncology (SSO-ASTRO) margin consensus ('no ink on tumour' for invasive and 2 mm for ductal carcinoma in situ [DCIS]) and the Association of Breast Surgery (ABS) consensus (1 mm for invasive and DCIS), we report on current margin practice and unit infrastructure in the UK and Ireland and describe how these factors impact on re-excision rates.Methods A trainee collaborative-led multicentre prospective study was conducted in the UK and Ireland between 1st February and 31st May 2016. Data were collected on consecutive BCT patients and on local infrastructure and policies.Results A total of 79 sites participated in the data collection (75% screening units; average 372 cancers annually, range 70-900). For DCIS, 53.2% of units accept 1 mm and 38% accept 2-mm margins. For invasive disease 77.2% accept 1 mm and 13.9% accept 'no ink on tumour'. A total of 2858 patients underwent BCT with a mean re-excision rate of 17.2% across units (range 0-41%). The re-excision rate would be reduced to 15% if all units applied SSO-ASTRO guidelines and to 14.8% if all units followed ABS guidelines. Of those who required re-operation, 65% had disease present at margin.Conclusion There continues to be large variation in margin policy and re-excision rates across units. Altering margin policies to follow either SSO-ASTRO or ABS guidelines would result in a modest reduction in the national re-excision rate. Most re-excisions are for involved margins rather than close margins.
dc.formatPrint-Electronic
dc.format.extent315 - 324
dc.languageeng
dc.language.isoeng
dc.subjectHumans
dc.subjectCarcinoma, Ductal, Breast
dc.subjectCarcinoma, Intraductal, Noninfiltrating
dc.subjectBreast Neoplasms
dc.subjectTreatment Outcome
dc.subjectMastectomy, Segmental
dc.subjectReoperation
dc.subjectProspective Studies
dc.subjectConsensus
dc.subjectGuideline Adherence
dc.subjectQuality Indicators, Health Care
dc.subjectIreland
dc.subjectFemale
dc.subjectPractice Guidelines as Topic
dc.subjectHealthcare Disparities
dc.subjectPractice Patterns, Physicians'
dc.subjectUnited Kingdom
dc.subjectMargins of Excision
dc.titleCurrent margin practice and effect on re-excision rates following the publication of the SSO-ASTRO consensus and ABS consensus guidelines: a national prospective study of 2858 women undergoing breast-conserving therapy in the UK and Ireland.
dc.typeJournal Article
dcterms.dateAccepted2017-07-20
rioxxterms.versionofrecord10.1016/j.ejca.2017.07.032
rioxxterms.licenseref.startdate2017-10
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfEuropean journal of cancer (Oxford, England : 1990)
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/Royal Marsden Clinical Units
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/Royal Marsden Clinical Units
pubs.publication-statusPublished
pubs.volume84
pubs.embargo.termsNot known
dc.contributor.icrauthorMarsden,en


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