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The Glioma International Case-Control Study: A Report From the Genetic Epidemiology of Glioma International Consortium.

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Publication Date
2016-01
ICR Author
Houlston, Richard
Author
Amirian, ES
Armstrong, GN
Zhou, R
Lau, CC
Claus, EB
Barnholtz-Sloan, JS
Il'yasova, D
Schildkraut, J
Ali-Osman, F
Sadetzki, S
Johansen, C
Houlston, RS
Jenkins, RB
Lachance, D
Olson, SH
Bernstein, JL
Merrell, RT
Wrensch, MR
Davis, FG
Lai, R
Shete, S
Amos, CI
Scheurer, ME
Aldape, K
Alafuzoff, I
Brännström, T
Broholm, H
Collins, P
Giannini, C
Rosenblum, M
Tihan, T
Melin, BS
Bondy, ML
Type
Journal Article
Metadata
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Abstract
Decades of research have established only a few etiological factors for glioma, which is a rare and highly fatal brain cancer. Common methodological challenges among glioma studies include small sample sizes, heterogeneity of tumor subtypes, and retrospective exposure assessment. Here, we briefly describe the Glioma International Case-Control (GICC) Study (recruitment, 2010-2013), a study being conducted by the Genetic Epidemiology of Glioma International Consortium that integrates data from multiple data collection sites, uses a common protocol and questionnaire, and includes biospecimen collection. To our knowledge, the GICC Study is the largest glioma study to date that includes collection of blood samples, which will allow for genetic analysis and interrogation of gene-environment interactions.
URL
https://repository.icr.ac.uk/handle/internal/1845
Collections
  • Genetics and Epidemiology
Version of record
10.1093/aje/kwv235
Subject
Humans
Glioma
Genetic Predisposition to Disease
Incidence
Risk Factors
Case-Control Studies
Retrospective Studies
International Cooperation
Adolescent
Adult
Aged
Aged, 80 and over
Middle Aged
Female
Male
Young Adult
Molecular Epidemiology
Gene-Environment Interaction
Research team
Cancer Genomics
Language
eng
Date accepted
2015-06-03
License start date
2016-01
Citation
American journal of epidemiology, 2016, 183 (2), pp. 85 - 91

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