The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)?
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The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)? Lobular carcinoma in situ was first described over 60 years ago. Despite the long history, it continues to pose significant difficulties in screening, diagnosis, management and treatment. This is partly due its multi-focal and bilateral presentation, an incomplete understanding of its biology and natural history and perpetuation of misconceptions gathered over the last decades. In this review, the working group on behalf of EUSOMA has attempted to summarise the current thinking and management of this interesting lesion. (c) 2006 Elsevier Ltd. All rights reserved.
Comparative genomic hybridization; preinvasive breast disease; surgical-adjuvant-breast; term follow-up; e-cadherin; female breast; conservative surgery; excisional biopsy; histological type; local recurrence
Molecular & Population Genetics
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EUROPEAN JOURNAL OF CANCER, 2006, 42 (14), pp. 2205 - 2211