Now showing items 1-2 of 2

    • Five endometrial cancer risk loci identified through genome-wide association analysis. 

      Cheng, TH; Thompson, DJ; O'Mara, TA; Painter, JN; Glubb, DM; Flach, S; Lewis, A; French, JD; Freeman-Mills, L; Church, D; Gorman, M; Martin, L; National Study of Endometrial Cancer Genetics Group (NSECG); Hodgson, S; Webb, PM; Australian National Endometrial Cancer Study Group (ANECS); Attia, J; Holliday, EG; McEvoy, M; Scott, RJ; Henders, AK; Martin, NG; Montgomery, GW; Nyholt, DR; Ahmed, S; Healey, CS; Shah, M; Dennis, J; Fasching, PA; Beckmann, MW; Hein, A; Ekici, AB; Hall, P; Czene, K; Darabi, H; Li, J; Dörk, T; Dürst, M; Hillemanns, P; Runnebaum, I; Amant, F; Schrauwen, S; Zhao, H; Lambrechts, D; Depreeuw, J; Dowdy, SC; Goode, EL; Fridley, BL; Winham, SJ; Njølstad, TS; Salvesen, HB; Trovik, J; Werner, HM; Ashton, K; Otton, G; Proietto, T; Liu, T; Mints, M; Tham, E; RENDOCAS; Consortium, C; Jun Li, M; Yip, SH; Wang, J; Bolla, MK; Michailidou, K; Wang, Q; Tyrer, JP; Dunlop, M; Houlston, R; Palles, C; Hopper, JL; AOCS Group; Peto, J; Swerdlow, AJ; Burwinkel, B; Brenner, H; Meindl, A; Brauch, H; Lindblom, A; Chang-Claude, J; Couch, FJ; Giles, GG; Kristensen, VN; Cox, A; Cunningham, JM; Pharoah, PDP; Dunning, AM; Edwards, SL; Easton, DF; Tomlinson, I; Spurdle, AB (2016-06)
      We conducted a meta-analysis of three endometrial cancer genome-wide association studies (GWAS) and two follow-up phases totaling 7,737 endometrial cancer cases and 37,144 controls of European ancestry. Genome-wide imputation ...
    • Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer. 

      Painter, JN; O'Mara, TA; Marquart, L; Webb, PM; Attia, J; Medland, SE; Cheng, T; Dennis, J; Holliday, EG; McEvoy, M; Scott, RJ; Ahmed, S; Healey, CS; Shah, M; Gorman, M; Martin, L; Hodgson, SV; Beckmann, MW; Ekici, AB; Fasching, PA; Hein, A; Rübner, M; Czene, K; Darabi, H; Hall, P; Li, J; Dörk, T; Dürst, M; Hillemanns, P; Runnebaum, IB; Amant, F; Annibali, D; Depreeuw, J; Lambrechts, D; Neven, P; Cunningham, JM; Dowdy, SC; Goode, EL; Fridley, BL; Winham, SJ; Njølstad, TS; Salvesen, HB; Trovik, J; Werner, HMJ; Ashton, KA; Otton, G; Proietto, A; Mints, M; Tham, E; Bolla, MK; Michailidou, K; Wang, Q; Tyrer, JP; Hopper, JL; Peto, J; Swerdlow, AJ; Burwinkel, B; Brenner, H; Meindl, A; Brauch, H; Lindblom, A; Chang-Claude, J; Couch, FJ; Giles, GG; Kristensen, VN; Cox, A; Pharoah, PDP; Tomlinson, I; Dunning, AM; Easton, DF; Thompson, DJ; Spurdle, AB; AOCS Group; for RENDOCAS; National Study of Endometrial Cancer Genetics Group (NSECG); Australian National Endometrial Cancer Study Group (ANECS) (2016-11)
      Background The strongest known risk factor for endometrial cancer is obesity. To determine whether SNPs associated with increased body mass index (BMI) or waist-hip ratio (WHR) are associated with endometrial cancer risk, ...