Browsing Breast Cancer Research by subject "p21-Activated Kinases"
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Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. (2018-07-09)Endocrine therapy resistance invariably develops in advanced estrogen receptor-positive (ER+) breast cancer, but the underlying mechanisms are largely unknown. We have identified C-terminal SRC kinase (CSK) as a critical ...