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dc.contributor.authorKalemis, A
dc.contributor.authorBinnie, D
dc.contributor.authorBailey, DL
dc.contributor.authorFlower, MA
dc.contributor.authorOtt, RJ
dc.date.accessioned2018-07-27T15:28:13Z
dc.date.issued2003-06-07
dc.identifier11
dc.identifier.citationPHYSICS IN MEDICINE AND BIOLOGY, 2003, 48 pp. 1539 - 1549
dc.identifier.issn0031-9155
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/2206
dc.identifier.eissn1361-6560en_US
dc.identifier.doi10.1088/0031-9155/48/11/304en_US
dc.description.abstractComparison of two medical images often requires image scaling as a preprocessing step. This is usually done with the scaling-to-the-mean or scaling-to-the-maximum techniques which, under certain circumstances, in quantitative applications may contribute a significant amount of bias. In this paper, we present a simple scaling method which assumes only that the most predominant values in the corresponding images belong to their background structure. The ratio of the two images to be compared is calculated and its frequency histogram is plotted. The scaling factor is given by the position of the peak in this histogram which belongs to the background structure. The method was tested against the traditional scaling-to-the-mean technique on simulated planar gamma-camera images which were compared using pixelwise statistical parametric tests. Both sensitivity and specificity for each condition were measured over a range of different contrasts and sizes of inhomogeneity for the two scaling techniques. The new method was found to preserve sensitivity in all cases while the traditional technique resulted in significant degradation of sensitivity in certain cases.
dc.format.extent1539 - 1549
dc.languageeng
dc.language.isoeng
dc.publisherIOP PUBLISHING LTD
dc.titleScaling images using their background ratio. An application in statistical comparisons of images
dc.typeJournal Article
rioxxterms.versionofrecord10.1088/0031-9155/48/11/304
rioxxterms.licenseref.startdate2003-06-07en_US
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfPHYSICS IN MEDICINE AND BIOLOGY
pubs.notesaffiliation: Kalemis, A (Reprint Author), Canc Res Inst, Dept Phys, Downs Rd, Sutton SM2 5PT, Surrey, England. Canc Res Inst, Dept Phys, Sutton SM2 5PT, Surrey, England. Royal N Shore Hosp, Dept Nucl Med, St Leonards, NSW 2065, Australia. Univ London Imperial Coll Sci & Technol, Blackett Lab, London SW7 2BW, England. Royal Marsden Hosp, Dept Phys, Sutton SM2 5PT, Surrey, England. article-number: PII S0031-9155(03)59942-0 keywords-plus: PET IMAGES; ACTIVATION; BRAIN research-areas: Engineering; Radiology, Nuclear Medicine & Medical Imaging web-of-science-categories: Engineering, Biomedical; Radiology, Nuclear Medicine & Medical Imaging author-email: [email protected] researcherid-numbers: Bailey, Dale/A-3359-2012 number-of-cited-references: 8 times-cited: 6 usage-count-last-180-days: 0 usage-count-since-2013: 1 journal-iso: Phys. Med. Biol. doc-delivery-number: 690RD unique-id: ISI:000183562000004 da: 2018-07-27
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Radioisotope Physics
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Radioisotope Physics
pubs.volume48en_US
pubs.embargo.termsNot known
icr.researchteamRadioisotope Physicsen_US
dc.contributor.icrauthorKalemis, Antonien
dc.contributor.icrauthorOtt, Roberten
dc.contributor.icrauthorFlower,en


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