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dc.contributor.authorSchwartz, GF
dc.contributor.authorBartelink, H
dc.contributor.authorBurstein, HJ
dc.contributor.authorCady, B
dc.contributor.authorCataliotti, L
dc.contributor.authorFentiman, IS
dc.contributor.authorHolland, R
dc.contributor.authorHughes, KS
dc.contributor.authorMasood, S
dc.contributor.authorMcCormick, B
dc.contributor.authorPalazzo, JA
dc.contributor.authorPressman, PI
dc.contributor.authorReis-Filho, J
dc.contributor.authorPusztai, L
dc.contributor.authorRutgers, EJT
dc.contributor.authorSeidman, AD
dc.contributor.authorSolin, LJ
dc.contributor.authorSparano, JA
dc.date.accessioned2018-08-08T10:11:30Z
dc.identifier4
dc.identifier.citationBREAST JOURNAL, 18 pp. 303 - 311
dc.identifier.issn1075-122X
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/2300
dc.identifier.doi10.1111/j.1524-4741.2012.01264.x
dc.description.abstractA consensus conference was held in order to provide guidelines for the use of adjuvant therapy in patients with Stage I carcinoma of the breast, using traditional information, such as tumor size, microscopic character, Nottingham index, patient age and co-morbidities, but also incorporating steroid hormone and Her-2-neu data as well as other immunohistochemical markers. The role of the genetic analysis of breast cancer and proprietary gene prognostic signatures was discussed, along with the molecular profiling of breast cancers into several groups that may predict prognosis. These molecular data are not currently sufficiently mature to make them part of decision making algorithms of recommendations for the treatment of individual patients.
dc.format.extent303 - 311
dc.languageeng
dc.language.isoeng
dc.publisherWILEY-BLACKWELL
dc.titleAdjuvant Therapy in Stage I Carcinoma of the Breast: The Influence of Multigene Analyses and Molecular Phenotyping
dc.typeJournal Article
rioxxterms.versionofrecord10.1111/j.1524-4741.2012.01264.x
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfBREAST JOURNAL
pubs.notesaffiliation: Schwartz, GF (Reprint Author), Breast Care Ctr, Philadelphia, PA 19107 USA. Schwartz, Gordon F., Breast Care Ctr, Philadelphia, PA 19107 USA. Palazzo, Juan A., Jefferson Med Coll, Dept Pathol, Philadelphia, PA 19107 USA. Bartelink, Harry, Antoni Van Leeuwenhoek Ziekenhuis, Inst Canc, NL-1066 CX Amsterdam, Netherlands. Burstein, Harold J., Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA. Cataliotti, Luigi, Univ Florence, I-50134 Florence, Italy. Fentiman, Ian S., Guys Hosp, London SE1 9RT, England. Holland, Roland, Univ Nijmegen Hosp, Natl Expert & Training Ctr Breast Canc Screening, NL-6500 HB Nijmegen, Netherlands. Hughes, Kevin S., Massachusetts Gen Hosp, Avon Comprehens Breast Evaluat Ctr, Boston, MA 02114 USA. Masood, Shahla, Univ Florida, Hlth Sci Ctr, Jacksonville, FL 32209 USA. McCormick, Beryl, Mem Sloan Kettering Canc Ctr, Dept Radiat Oncol, New York, NY 10021 USA. Pressman, Peter I., New York Presbyterian Hosp, New York, NY USA. Reis-Filho, Jorge, Inst Canc Res, Chester Beatty Labs, Breakthrough Breast Canc Res Ctr, London SW3 6JB, England. Pusztai, Lajos, UT MD Anderson Canc Ctr, Dept Breast Med Oncol, Houston, TX USA. Rutgers, Emiel J. T., Antoni Van Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Surg, NL-1066 CX Amsterdam, Netherlands. Seidman, Andrew D., Cornell Univ, Breast Canc Med Serv, Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA. Seidman, Andrew D., Cornell Univ, Weill Med Coll, New York, NY 10021 USA. Solin, Lawrence J., Albert Einstein Med Ctr, Dept Radiat Oncol, Philadelphia, PA 19141 USA. Sparano, Joseph A., Albert Einstein Coll Med, Dept Med Oncol, Bronx, NY 10467 USA. keywords: adjuvant therapy; breast carcinoma; estrogen receptors; gene analysis; Her-2-neu; progesterone receptors; Ki-67 keywords-plus: CANCER; EXPRESSION; RECURRENCE; RISK; CHEMOTHERAPY; PREDICTION; PROGNOSIS; TAMOXIFEN; SUBTYPES; MARKERS research-areas: Oncology; Obstetrics & Gynecology web-of-science-categories: Oncology; Obstetrics & Gynecology author-email: [email protected] orcid-numbers: Hughes, Kevin/0000-0003-4084-6484 Mc Cormick, Beryl/0000-0002-4550-0565 number-of-cited-references: 33 times-cited: 7 usage-count-last-180-days: 0 usage-count-since-2013: 1 journal-iso: Breast J. doc-delivery-number: 968HP unique-id: ISI:000305968600003 da: 2018-08-08
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams/Molecular Pathology
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams/Molecular Pathology
pubs.volume18
pubs.embargo.termsNot known
icr.researchteamMolecular Pathologyen_US
dc.contributor.icrauthorReis-Filho, Jorge Sergioen


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