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dc.contributor.authorWeller, D
dc.contributor.authorColeman, D
dc.contributor.authorRobertson, R
dc.contributor.authorButler, P
dc.contributor.authorMelia, J
dc.contributor.authorCampbell, C
dc.contributor.authorParker, R
dc.contributor.authorPatnick, J
dc.contributor.authorMoss, S
dc.date.accessioned2018-08-30T13:42:04Z
dc.date.issued2007-12-11
dc.identifier12
dc.identifier.citationBRITISH JOURNAL OF CANCER, 2007, 97 pp. 1601 - 1605
dc.identifier.issn0007-0920
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/2441
dc.identifier.doi10.1038/sj.bjc.6604089
dc.description.abstractAn evaluation of the second round of faecal occult blood ( FOB) screening in the English site of the UK Colorectal Cancer Screening Pilot ( comprising the Bowel Cancer Screening Pilot based in Rugby, general practices in four Primary Care Trusts, and their associated hospitals) was carried out. A total of 127746 men and women aged 50-69 and registered in participating general practices were invited to participate. In all, 15.9% were new invitees not included in the previous round. A total of 52.1% of invitees returned a screening kit. Uptake varied with gender, age, and level of deprivation; was lower than in the first round (51.9 vs 58.5% P<0.0001), but was high (81.1%) in those who had participated in the first round with a negative result. Test positivity was 1.77%, significantly higher than in the first round, and the detection rate of neoplasia similar (5.67 per 1000), resulting in a lower positive predictive value. The sensitivity of FOBt in the first round was estimated as 57.7-64.4%. There was a significant impact on workload, particularly on endoscopy services. The cancer detection rate (0.94 per 1000) was lower than in the first round. Effort will be required to minimise inequalities in uptake, and to ensure adequate capacity of endoscopy services.
dc.format.extent1601 - 1605
dc.languageeng
dc.language.isoeng
dc.publisherNATURE PUBLISHING GROUP
dc.titleThe UK colorectal cancer screening pilot: results of the second round of screening in England
dc.typeJournal Article
rioxxterms.versionofrecord10.1038/sj.bjc.6604089
rioxxterms.licenseref.startdate2007-12-11
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfBRITISH JOURNAL OF CANCER
pubs.notesaffiliation: Weller, D (Reprint Author), Univ Edinburgh, 20 W Richmond St, Edinburgh EH8 9DX, Midlothian, Scotland. Weller, D.; Robertson, R.; Campbell, C., Univ Edinburgh, Edinburgh EH8 9DX, Midlothian, Scotland. Coleman, D.; Butler, P.; Melia, J.; Moss, S., Inst Canc Res, Canc Screening Evaluat Unit, Sutton SM2 5NG, Surrey, England. Parker, R., Hosp St Cross, Bowel Canc Screening Unit, Rugby CV22 5PX, England. Patnick, J., NHS Canc Screening Programmes, Sheffield S4 7UQ, S Yorkshire, England. keywords: colorectal neoplasms; mass screening; faecal occult blood keywords-plus: OCCULT BLOOD-TEST; POPULATION research-areas: Oncology web-of-science-categories: Oncology author-email: [email protected] number-of-cited-references: 16 times-cited: 147 usage-count-last-180-days: 0 usage-count-since-2013: 9 journal-iso: Br. J. Cancer doc-delivery-number: 240ZF unique-id: ISI:000251626000001 oa: gold_or_bronze da: 2018-08-30
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams/Cancer Screening Evaluation Unit (DoH)
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams/Cancer Screening Evaluation Unit (DoH)
pubs.volume97
pubs.embargo.termsNot known
icr.researchteamCancer Screening Evaluation Unit (DoH)en_US
dc.contributor.icrauthorMoss, Susan Maryen
dc.contributor.icrauthorMelia, Janeen
dc.contributor.icrauthorColeman, Derecken


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