Allosteric regulation of chaperonins
Publication Date
2005-12ICR Author
Author
Horovitz, A
Willison, KR
Type
Journal Article
Metadata
Show full item recordAbstract
Chaperonins are molecular machines that facilitate protein folding by undergoing energy (ATP)-dependent movements that are coordinated in time and space by complex allosteric regulation. Recently, progress has been made in describing the various functional (allosteric) states of these machines, the pathways by which they interconvert, and the coupling between allosteric transitions and protein folding reactions. However, various mechanistic issues remain to be resolved.
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Version of record
Research team
Chromatin Regulation
Language
English
License start date
2005-12
Citation
CURRENT OPINION IN STRUCTURAL BIOLOGY, 2005, 15 pp. 646 - 651
Publisher
CURRENT BIOLOGY LTD