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dc.contributor.authorMoss, S
dc.contributor.authorGray, A
dc.contributor.authorLegood, R
dc.contributor.authorVessey, M
dc.contributor.authorPatnick, J
dc.contributor.authorKitchener, H
dc.contributor.authorPapilloma, LBCH
dc.date.accessioned2018-09-04T11:48:13Z
dc.date.issued2006-01-14
dc.identifier7533
dc.identifier.citationBRITISH MEDICAL JOURNAL, 2006, 332 pp. 83 - 85
dc.identifier.issn0959-8146
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/2535
dc.identifier.doi10.1136/bmj.38701.440961.7C
dc.description.abstractObjective To assess the effect of introducing testing for human papillomavirus combined with liquid based cytology in women with low grade cytological abnormalities. Design Observational before and after study. Setting Three cervical screening laboratories, England. Participants 5654 women aged 20-64 with low grade cytological abnormalities found at routine cervical screening in a pilot; 5254 similar women in the period before the pilot. Interventions Human papillomavirus testing combined with liquid based cytology in the management of women with borderline or mildly dyskaryotic cervical smear results compared with conventional smear tests, with immediate referral colposcopy of Women positive for human papillomavirus. Results 57.9% (3187/5506) of women tested in the pilot were positive for human papillomavirus. The rate of repeat smears fell by 74%, but the rate of referral to colposcopy for low grade cytological abnormalities more than doubled. The estimated negative predictive value of human papillomavirus testing varied between 93.8% and 99.7%. Conclusion The addition of testing for human papillomavirus in women with low grade cytological abnormalities resulted in a reduction in the rate of repeat smears, but an increase in rates of referral to colposcopy.
dc.format.extent83 - 85
dc.languageeng
dc.language.isoeng
dc.publisherB M J PUBLISHING GROUP
dc.titleEffect of testing for human papillomavirus as a triage during screening for cervical cancer: observational before and after study
dc.typeJournal Article
rioxxterms.versionofrecord10.1136/bmj.38701.440961.7C
rioxxterms.licenseref.startdate2006-01-14
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfBRITISH MEDICAL JOURNAL
pubs.notesaffiliation: Moss, S (Reprint Author), Inst Canc Res, Canc Screening Evaluat Unit, Sutton SM2 5NG, Surrey, England. Inst Canc Res, Canc Screening Evaluat Unit, Sutton SM2 5NG, Surrey, England. Univ Oxford, Dept Publ Hlth, Hlth Econ Res Ctr, Oxford OX3 7LF, England. Univ Oxford, Dept Publ Hlth, Unit Hlth Care Epidemiol, Oxford OX3 7LF, England. NHS Canc Screening Programmes, Sheffield S10 3TH, S Yorkshire, England. Univ Manchester, St Marys Hosp, Manchester M13 0JH, Lancs, England. keywords-plus: WOMEN research-areas: General & Internal Medicine web-of-science-categories: Medicine, General & Internal author-email: [email protected] number-of-cited-references: 5 times-cited: 52 usage-count-last-180-days: 0 usage-count-since-2013: 0 journal-iso: Br. Med. J. doc-delivery-number: 004UE unique-id: ISI:000234777000018 oa: gold_or_bronze da: 2018-09-04
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams/Cancer Screening Evaluation Unit (DoH)
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Closed research teams/Cancer Screening Evaluation Unit (DoH)
pubs.volume332
pubs.embargo.termsNot known
icr.researchteamCancer Screening Evaluation Unit (DoH)en_US
dc.contributor.icrauthorMoss, Susan Maryen


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