dc.contributor.author | Moss, S | |
dc.contributor.author | Thomas, I | |
dc.contributor.author | Evans, A | |
dc.contributor.author | Thomas, B | |
dc.contributor.author | Johns, L | |
dc.contributor.author | Grp, TM | |
dc.date.accessioned | 2018-09-07T09:01:46Z | |
dc.date.issued | 2005-03-14 | |
dc.identifier | 5 | |
dc.identifier.citation | BRITISH JOURNAL OF CANCER, 2005, 92 pp. 949 - 954 | |
dc.identifier.issn | 0007-0920 | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/2578 | |
dc.identifier.doi | 10.1038/sj.bjc.6602396 | |
dc.description.abstract | Debate continues over the effectiveness of screening by mammography in women below age 50. We report here on results of screening in the first 10 years of a randomised trial to study the effect on breast cancer mortality of invitation to annual mammography from age 40 to 41 compared to first invitation to the 3-yearly UK national programme at age 50-52. The trial is taking place in 23 NHS breast screening centres. Between 1991 and 1997, 160 921 women were randomised in the ratio 1 : 2 to intervention and control arms. Screening is by two views at first screen and single view subsequently; data on screening up to and including round five are now complete. Uptake of invitation to screening is between 68 and 70% at all but the latest screening rounds. Rates of referral for assessment are 4.6% at first screen and 3.4% at subsequent screens. Invasive cancer detection rates are 0.09% at first screen, and similar at rescreens until the sixth and later screens. There is little evidence of regular mammography in the trial control arm. The setting of this trial within the NHS breast screening programme should ensure applicability of results to a national programme. | |
dc.format.extent | 949 - 954 | |
dc.language | eng | |
dc.language.iso | eng | |
dc.publisher | NATURE PUBLISHING GROUP | |
dc.title | Randomised controlled trial of mammographic screening in women from age 40: results of screening in the first 10 years | |
dc.type | Journal Article | |
rioxxterms.versionofrecord | 10.1038/sj.bjc.6602396 | |
rioxxterms.licenseref.startdate | 2005-03-14 | |
rioxxterms.type | Journal Article/Review | |
dc.relation.isPartOf | BRITISH JOURNAL OF CANCER | |
pubs.notes | affiliation: Moss, S (Reprint Author), Inst Canc Res, Canc Screening Evaluat Unit, Brookes Lawley Bldg,15 Cotswold Rd, Sutton SM2 5NG, Surrey, England. Inst Canc Res, Canc Screening Evaluat Unit, Sutton SM2 5NG, Surrey, England. City Hosp, Natl Breast Screening Training Ctr, Nottingham NG5 1PB, England. Jarvis Breast Screening Diagnost & Natl Training, Surrey GU1 1LJ, England. keywords: breast; screening; mammography; age; trial keywords-plus: BREAST-CANCER; UK TRIAL; MORTALITY research-areas: Oncology web-of-science-categories: Oncology author-email: [email protected] number-of-cited-references: 12 times-cited: 29 usage-count-last-180-days: 0 usage-count-since-2013: 3 journal-iso: Br. J. Cancer doc-delivery-number: 908YY unique-id: ISI:000227827300026 oa: gold_or_bronze da: 2018-09-06 | |
pubs.notes | Not known | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Closed research teams | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Closed research teams/Cancer Screening Evaluation Unit (DoH) | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Closed research teams | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Closed research teams/Cancer Screening Evaluation Unit (DoH) | |
pubs.volume | 92 | |
pubs.embargo.terms | Not known | |
icr.researchteam | Cancer Screening Evaluation Unit (DoH) | en_US |
dc.contributor.icrauthor | Moss, Susan Mary | en |