Publications Repository

Publications Repository

View item 
  •   Home
  • ICR Divisions
  • Closed Research Teams
  • View item
  • Home
  • ICR Divisions
  • Closed Research Teams
  • View item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Radiotherapy for malignant gliomas in the elderly

Thumbnail
Date
2003
ICR Author
Brada, Michael
Author
Brada, M
Stenning, SP
Type
Journal Article
Metadata
Show full item record
Abstract
While fractionated external beam radiotherapy remains the principal treatment in patients with histologically verified malignant glioma, its use in older patients and in patients with adverse prognostic features has not been subject to randomized studies. Hypofractionated partial brain irradiation offers a short, well-tolerated treatment with a palliative benefit for patients with a predicted median survival of less than 6 months. To assess its true efficacy in terms of survival and quality-of-life gain requires a formal randomized comparison with supportive care either alone or in combination with palliative chemotherapy and with radical radiotherapy. On present evidence, palliative radiotherapy remains the appropriate treatment for older patients and those with adverse prognostic features, but the final choice should be based on the patient’s wishes moderated by the clinician’s perception of the gain of treatment.
URI
https://repository.icr.ac.uk/handle/internal/2664
DOI
https://doi.org/10.1053/j.seminoncol.2003.11.034
Collections
  • Closed Research Teams
Research team
Clinical Academic Radiotherapy (Brada)
Language
eng
License start date
2003
Citation
Seminars in Oncology, 2003, 30 pp. 63 - 67

Browse

All of ICR repositoryICR DivisionsBy issue dateAuthorsTitlesPublication TypesThis collectionBy issue dateAuthorsTitlesPublication Types
  • Login
  • Registered office: The Institute of Cancer Research, 123 Old Brompton Road, London, SW7 3RP
    A Charity, Not for Profit. Company Limited by Guarantee.
    Registered in England No. 534147. VAT Registration No. GB 849 0581 02.