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Synthesis of a novel dimeric bis-benzimidazole with site-selective DNA-binding properties

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Date
2002
ICR Author
Neidle, Stephen
Author
Sun, X-W
Neidle, S
Mann, J
Type
Journal Article
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Abstract
We describe the synthesis of bis(3-4-[2′-(4-methoxyphenyl)-3H,3′H-[5,5′]bibenzimidazolyl-2-yl]phenoxypropyl)methylamine 8, which has high affinity for the oligonucleotide sequence [A.T]4-[G.C]-[A.T]4.
URI
https://repository.icr.ac.uk/handle/internal/2756
DOI
https://doi.org/10.1016/S0040-4039(02)01595-2
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  • Other ICR Research
Language
eng
License start date
2002
Citation
Tetrahedron Letters, 2002, 43 pp. 7239 - 7241

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