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dc.contributor.authorVaughan, Ken_US
dc.contributor.authorWilman, DEVen_US
dc.contributor.authorWheelhouse, RTen_US
dc.contributor.authorStevens, MFGen_US
dc.date.accessioned2018-09-18T14:40:19Z
dc.date.issued2002-04en_US
dc.identifier4en_US
dc.identifier.citationMAGNETIC RESONANCE IN CHEMISTRY, 2002, 40 pp. 300 - 302en_US
dc.identifier.issn0749-1581en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/2789
dc.identifier.doi10.1002/mrc.994en_US
dc.description.abstractA series of 3-substituted 1,2,3-benzotriazin-4-ones, 1 and 2, were synthesized by standard methods and the N-15 NMR spectra were recorded. All spectra were obtained using the natural abundance of the nitrogen-15 isotope. The chemical shifts appear in the normal range for N-1, N-2 and N-3 of the triazine ring, and also correlate with the chemical shifts in the spectra of the imidazolotriazinone, 4, and the imidazolotetrazinone, 5. Significantly, the spectra of la, 2 and 4, recorded with full NOE, show inversion of the singlet assigned to N-3, demonstrating that these compounds exist in the tautomeric form shown. The structure of the 4-iminobenzotriazinone (3) was confirmed by this N-15 NMR analysis. The spectrum shows a signal for the NH-bearing imino-nitrogen atom, which is an inverted singlet in the NOE spectrum, whereas the signal from the N-3 atom of 3 is not inverted in the NOE spectrum. Copyright (C) 2002 John Wiley Sons, Ltd.en_US
dc.format.extent300 - 302en_US
dc.titleA N-15 NMR investigation of a series of benzotriazinones and related antitumour heterocyclesen_US
dc.typeJournal Article
rioxxterms.versionofrecord10.1002/mrc.994en_US
rioxxterms.licenseref.startdate2002-04en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfMAGNETIC RESONANCE IN CHEMISTRYen_US
pubs.notesresearcherid-numbers: Wheelhouse, Richard/B-2519-2009 orcid-numbers: Wheelhouse, Richard/0000-0002-2250-3384 unique-id: ISI:000174490100009en_US
pubs.notesNot knownen_US
pubs.organisational-group/ICR
pubs.volume40en_US
pubs.embargo.termsNot knownen_US
dc.contributor.icrauthorWheelhouse, Richarden_US


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