Now showing items 344-347 of 347

    • Visualizing cellular imaging data using PhenoPlot. 

      Sailem, HZ; Sero, JE; Bakal, C (2015-01-08)
      Visualization is essential for data interpretation, hypothesis formulation and communication of results. However, there is a paucity of visualization methods for image-derived data sets generated by high-content analysis ...
    • Warthin Tumor-Like Mucoepidermoid Carcinoma. 

      Heatley, N; Harrington, KJ; Thway, K (2018-02)
      Mucoepidermoid carcinoma (MEC) shows a wide morphologic spectrum, including epithelium with oncocytic or squamous metaplastic changes overlying a prominent cystic architecture, as well as tumor-associated lymphoid tissue. ...
    • WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer. 

      Ertay, A; Liu, H; Liu, D; Peng, P; Hill, C; Xiong, H; Hancock, D; Yuan, X; Przewloka, MR; Coldwell, M; Howell, M; Skipp, P; Ewing, RM; Downward, J; Wang, Y (2020-11-21)
      Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer that lacks the oestrogen receptor, progesterone receptor and human epidermal growth factor receptor 2, making it difficult to target ...
    • WDR5, BRCA1, and BARD1 Co-regulate the DNA Damage Response and Modulate the Mesenchymal-to-Epithelial Transition during Early Reprogramming. 

      Peñalosa-Ruiz, G; Bousgouni, V; Gerlach, JP; Waarlo, S; van de Ven, JV; Veenstra, TE; Silva, JCR; van Heeringen, SJ; Bakal, C; Mulder, KW; Veenstra, GJC (2019-04)
      Differentiated cells are epigenetically stable, but can be reprogrammed to pluripotency by expression of the OSKM transcription factors. Despite significant effort, relatively little is known about the cellular requirements ...