Now showing items 1-4 of 4

    • Alternative splicing in prostate cancer. 

      Paschalis, A; Sharp, A; Welti, JC; Neeb, A; Raj, GV; Luo, J; Plymate, SR; de Bono, JS (2018-11)
      Androgen receptor (AR) splice variants (AR-Vs) have been implicated in the development and progression of metastatic prostate cancer. AR-Vs are truncated isoforms of the AR, a subset of which lack a ligand-binding domain ...
    • An Evolving Algorithm to Select and Sequence Therapies in EGFR Mutation-positive NSCLC: A Strategic Approach. 

      Melosky, B; Popat, S; Gandara, DR (2018-01)
      The optimal treatment sequence for patients with metastatic epidermal growth factor receptor (EGFR) mutation-positive (EGFR-M<sup>+</sup>) non-small-cell lung cancer (NSCLC) continues to evolve, related largely to an ...
    • Circulating tumor DNA-From bench to bedside. 

      Lim, JSJ; Janku, F; Yap, TA (2017-05)
      In the era of personalized medicine, tumor sampling is paramount to enable the assessment of actionable molecular aberrations to help rationalize and guide treatment decisions. Longitudinal tracking of such aberrations may ...
    • International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis. 

      Scott, AJ; Alexander, JL; Merrifield, CA; Cunningham, D; Jobin, C; Brown, R; Alverdy, J; O'Keefe, SJ; Gaskins, HR; Teare, J; Yu, J; Hughes, DJ; Verstraelen, H; Burton, J; O'Toole, PW; Rosenberg, DW; Marchesi, JR; Kinross, JM (2019-09)
      <h4>Objective</h4>In this consensus statement, an international panel of experts deliver their opinions on key questions regarding the contribution of the human microbiome to carcinogenesis.<h4>Design</h4>International ...