Now showing items 1-2 of 2

    • Efficient Genotyping of KRAS Mutant Non-Small Cell Lung Cancer Using a Multiplexed Droplet Digital PCR Approach. 

      Pender, A; Garcia-Murillas, I; Rana, S; Cutts, RJ; Kelly, G; Fenwick, K; Kozarewa, I; Gonzalez de Castro, D; Bhosle, J; O'Brien, M; Turner, NC; Popat, S; Downward, J (2015-01)
      Droplet digital PCR (ddPCR) can be used to detect low frequency mutations in oncogene-driven lung cancer. The range of KRAS point mutations observed in NSCLC necessitates a multiplex approach to efficient mutation detection ...
    • Transplantation of discarded livers following viability testing with normothermic machine perfusion. 

      Mergental, H; Laing, RW; Kirkham, AJ; Perera, MTPR; Boteon, YL; Attard, J; Barton, D; Curbishley, S; Wilkhu, M; Neil, DAH; Hübscher, SG; Muiesan, P; Isaac, JR; Roberts, KJ; Abradelo, M; Schlegel, A; Ferguson, J; Cilliers, H; Bion, J; Adams, DH; Morris, C; Friend, PJ; Yap, C; Afford, SC; Mirza, DF (2020-06-16)
      There is a limited access to liver transplantation, however, many organs are discarded based on subjective assessment only. Here we report the VITTAL clinical trial ( number NCT02740608) outcomes, using ...