Now showing items 1-2 of 2

    • T-cell infiltration and clonality correlate with programmed cell death protein 1 and programmed death-ligand 1 expression in patients with soft tissue sarcomas. 

      Pollack, SM; He, Q; Yearley, JH; Emerson, R; Vignali, M; Zhang, Y; Redman, MW; Baker, KK; Cooper, S; Donahue, B; Loggers, ET; Cranmer, LD; Spraker, MB; Seo, YD; Pillarisetty, VG; Ricciotti, RW; Hoch, BL; McClanahan, TK; Murphy, E; Blumenschein, WM; Townson, SM; Benzeno, S; Riddell, SR; Jones, RL (2017-09)
      Patients with metastatic sarcomas have poor outcomes and although the disease may be amenable to immunotherapies, information regarding the immunologic profiles of soft tissue sarcoma (STS) subtypes is limited.The authors ...
    • Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease. 

      Popat, S; Hearle, N; Hogberg, L; Braegger, CP; O'Donoghue, D; Falth-Magnusson, K; Holmes, GKT; Howdle, PD; Jenkins, H; Johnston, S; Kennedy, NP; Kumar, PJ; Logan, RFA; Marsh, MN; Mulder, CJ; Torinsson Naluai, A; Sjoberg, K; Stenhammar, L; Walters, JRF; Jewell, DP; Houlston, RS (2002-03)
      Susceptibility to coeliac disease involves HLA and non-HLA-linked genes. The CTLA4/CD28 gene region encodes immune regulatory T-cell surface molecules and is a strong candidate as a susceptibility locus. We evaluated ...