Browsing Radiotherapy and Imaging by author "D'Arcy, James"
Now showing items 1-4 of 4
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Carbogen breathing increases prostate cancer oxygenation: a translational MRI study in murine xenografts and humans
(NATURE PUBLISHING GROUP, 2009-02-17)Hypoxia has been associated with poor local tumour control and relapse in many cancer sites, including carcinoma of the prostate. This translational study tests whether breathing carbogen gas improves the oxygenation of ... -
Dynamic contrast-enhanced magnetic resonance imaging is a poor measure of rectal cancer angiogenesis
(JOHN WILEY & SONS LTD, 2006-08)Background: The aim of this study was to investigate the use of magnetic resonance imaging (MRI) for non-invasive measurement of rectal cancer angiogenesis and hypoxia. Methods: Fifteen patients with rectal adenocarcinoma ... -
Hypoxia in prostate cancer: Correlation of bold-MRI with pimonidazole immunohistochemistry - Initial observations
(ELSEVIER SCIENCE INC, 2007-07-15)Purpose: To investigate the ability of blood oxygen level- dependent (BOLD) MRI to depict clinically significant prostate tumor hypoxia. Methods and Materials: Thirty-three patients with prostate carcinoma undergoing radical ... -
Reproducibility and Correlation Between Quantitative and Semiquantitative Dynamic and Intrinsic Susceptibility-Weighted MRI Parameters in the Benign and Malignant Human Prostate
(JOHN WILEY & SONS INC, 2010-07)Purpose: To assess the reproducibility of relaxivity- and susceptibility-based dynamic contrast-enhanced magnetic resonance imaging (MRI) in the benign and malignant prostate gland and to correlate the kinetic parameters ...